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p53 DINP1 Antibody

p53 DINP1 Antibody is available 1 time from Bioss primary unconjugated antibodies labs

bs-6146R | p53 DINP1 Antibody size: 0.1ml | 309.47 USD

Catalog number bs-6146R
Price 309.47 USD
Size 0.1ml
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Long name p53 DINP1 Primary Polyclonal Antibody
Also known as p53 DINP1 PAb
Category Primary Antibodies
Conjugation Unconjugated
Target Antigen p53 DINP1
Specificity This is a highly specific antibody against p53 DINP1.
Modification(s) None
Modification site(s) Unmodified antibody
Clonality Polyclonal antibody
Clone number Polyclonal antibody
Concentration 1ug per 1ul
Source This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p53 DINP1
Gene ID number 94241
Tested Applications WB, IHC-P, IF(IHC-P)
Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity Human, Mouse, Rat
Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.
Purification method This antibody was purified via Protein A.
Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names Tumor protein p53-inducible nuclear protein 1; TP53INP1; P53DINP1; SIP
Properties If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetp53 DINP1
Short name Anti-p53 DINP1
Technique Antibody
Host Rabbit (Oryctolagus cuniculus)
Isotype Immunoglobulin G (IgG)
Alternative name p53 DINP1 Polyclonal Antibody
Alternative technique antibodies
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Anti-p53 DINP1 | Technique alternative | 01011316338
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • p53
  • DINP1
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