Rabbit Polyclonal Serum Anti-Beta-Defensin-2 (HBD-2)
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Catalog numberDEF002
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PricePlease ask
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Size50 µl
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AvailabilityPlease contact us to check the availability
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ImmunogenSynthetic human-ß-Defensin-2 conjugated to bovine thyroglobulin, hBD-2: Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (MW 4328,2)
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Specificityß-Defensin-2 (human) hBD-2, no cross-reactivity with human beta-defensin-1 and human alpha-defensin-1 in dir. ELISA using 0,5 µg/well
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Species reactivityHuman
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Product presentationAntiserum lyophilised from 1 mM phosphate buffer (pH 7.0)
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Product categoryPrimary Antibody
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Antibody s raised inRabbit
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Antibody s isotypeSerum
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Antibody s clonepolyclonal
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Product is supplied aslyophilisate
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Recommended concentration for use1:5000 - 1:100000 dir. ELISA
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Protein concentrationN/A
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Positive controlSkin or oral mucosa
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Tested applicationsIHC(C, P), ELISA, RIA
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Recommended secondary reagentWe recommend the VECTASTAIN Elite ABC Kit Rabbit IgG (Ref. PK-6101) or BioPrime Universal Staining Kits (Ref. AE005 and DA005).
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Storage methodStore at -20'°C'
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UniProt numberGo to UniProt/SwissProt
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Litterature1. Harder J., Bartels J., Christophers E., and J.-M. Schröder (1997) Antibacterial peptide specific for Gram-negative Bacteria / also effective for Candida albicans. Nature 387; 861ff 2. Hiratsuka T., Nakazato M., Date Y., Ashitani J., Minematsu T, Chino N., and S. Matsukura (1998) Biochem. Biophys. Res. Comm. (Pharmacol.) 249; 943 ff
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TipsGentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin. Azide Free Serum for cell culture FBS fetal bovine serum. Filtered serum for sterility. The polyclonal serum contains no red or white blood cells or clotting factors; it is the blood plasma not including the fibrinogens. Serum includes all proteins and antibodies not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances like drugs and microorganisms. Plasmas on request.
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GroupPolyclonals and antibodies, Sera
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Serum should be stored at +5°C
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolHBD, DEFB4A, DEFB1, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
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Short nameResearch
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TechniquePolyclonal, Rabbit, anti-, serum, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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Alternative nameBeta-Defensin-2 (HBD-2)
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Alternative techniquepolyclonals, rabbit-anti, sera, antibodies
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Tissueserum
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Gene info
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Identity
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Gene
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Long gene namehemoglobin subunit delta
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Synonyms gene name
- hemoglobin, delta
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Hemoglobin subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namedefensin beta 4A
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Synonyms gene
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Synonyms gene name
- defensin, beta 2
- defensin, beta 4
- defensin, beta 4A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-08-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
- Defensins, beta
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefensin beta 1
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Synonyms gene name
- defensin, beta 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-05-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Defensins, beta
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 329-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-11
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR329 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namekeratin associated protein 13-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-21
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Entrez gene record
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Pubmed identfication
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Classification
- Keratin associated proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data