SU 16f

  • Catalog number
    B1081-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    5-[1,2-Dihydro-2-oxo-6-phenyl-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid
  • Description
    SU 16f is a potent, cell-permeable and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC₅₀ = 10 nM). It displays > 14-fold, > 229-fold and > 10000-fold selectivity over VEGFR2, FGFR1 and EGFR respectively. Inhibits proliferation of HUVEC and NIH3T3 cells in vitro (IC₅₀ = 0.11 μM).
  • CAS Number
    251356-45-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₂N₂O₃
  • Molecular Weight
    386.44
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>35 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent, cell-permeable and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD03452699
  • PubChem CID
    5329150
  • SMILES
    CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O
  • InChi
    nChI=1S/C24H22N2O3/c1-14-18(10-11-23(27)28)15(2)25-21(14)13-20-19-9-8-17(12-22(19)26-24(20)29)16-6-4-3-5-7-16/h3-9,12-13,25H,10-11H2,1-2H3,(H,26,29)(H,27,28)/b20-13-
  • InChi Key
    APYYTEJNOZQZNA-MOSHPQCFSA-N
  • MSDS Available
    Yes
  • Gene target
    16f  
  • Short name
    SU 16f
  • Alternative name
    SU 16f
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