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Gene info
Exodus 2 is one of several CC cytokine genes clustered on the p arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterised by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils.
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Gene names
SLC, CKb9, TCA4, 6Ckine, Ccl21b, Scya21, Scya21b, Scya21c, exodus-2, C-C motif chemokine 21c
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Antibodie s label
unlabelled serum
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Purity
Anti-mExodus-2 specific antibody was purified by affinity chromatography employing immobilized mExodus-2 matrix.
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Ab raised in
Rabbit
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Type
Polyclonal
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Antigen
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mExodus-2 (murine Exodus-2).
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Immuno application
ELISA, Western Blot, NELISAut
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Antibody advice
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mExodus-2 (100.0 ng/mL), a concentration of 9.0-10.0 ug/mL of this antibody is required. ELISA:To detect mExodus-2 by direct ELISA (using 100 μL/well antibody solution) a concentration of at least 0.5 ug/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant mExodus-2. Sandwich: To detect mExodus-2 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 ug/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Murine Exodus-2 (XP-5129Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mExodus-2.Western Blot:To detect mExodus-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant mExodus-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
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Keep at
Exodus-2 antibody is stable for at least 2 years from date of receipt at -20 grades C. The reconstituted antibody is stable for at least two weeks at 2-8 grades C. Frozen aliquots are stable for at least 6 months when stored at -20 grades C. Avoid repeated freeze-thaw cycles.
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Works with
Mouse
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Omim nr
317374807
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Ncbi nr
P86793
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Vial with antibody
Lyophilized
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NCBI GENE nr
65956
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GENE symbol
Ccl21c
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Antigene name
chemokine (C-C motif) ligand 21C (leucine)
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Source
Mus musculus
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Protein nr
P86793
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
