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anti-DRAM Antibody (NT)

anti-DRAM Antibody (NT) is available 1 time from Biovision labs

5075-100 | anti-DRAM Antibody (NT) size: DRAM Antibody (NT) | 471.67 USD

Catalog number 5075-100
Supplier Biovision
Price 471.67 USD
Size DRAM Antibody (NT)
1. Gene info
Identity 25645
Gene DRAM1
Long gene name DNA damage regulated autophagy modulator 1
Synonyms gene name
  • DNA-damage regulated autophagy modulator 1
Synonyms
  • FLJ11259
  • DRAM
Synonyms name
  • damage-regulated autophagy modulator
GenBank acession
  • BC018435
  • DA721965
Locus 12q23.2
Discovery year 2009-06-12
Entrez gene record 55332
Pubmed identfication
  • 16839881
RefSeq identity
  • NM_018370
Havana BLAST/BLAT OTTHUMG00000170447
2. Gene info
Identity 8024
Gene NTF4
Long gene name neurotrophin 4
Synonyms gene
  • NTF5
Synonyms gene name
  • neurotrophin 5 (neurotrophin 4/5)
Synonyms
  • NT-4/5
  • GLC1O
Synonyms name
  • neurotrophic factor 4
Locus 19q13.33
Discovery year 1992-10-15
Entrez gene record 4909
Pubmed identfication
  • 1496419
RefSeq identity
  • NM_006179
Classification
  • Neurotrophins
Havana BLAST/BLAT OTTHUMG00000191728
Product images
    #0#.jpeg
Target of this antibody: DRAM
Alternative names of antibody target: Damage-regulated autophagy modulator
Background information: Damage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles. It has been sμggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA, Bax, etc., and that the signaling pathways regulated by these genes promote a full cell death response. By itself, DRAM cannot induce apoptosis, but the fact that it is inactivated in certain cancers highlights the importance of DRAM and sμggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG1
This antibody reacts with: Human, mouse, rat
Immunogene sequence: DRAM antibody was raised against a 16 amino acid peptide from near the amino terminus of human DRAM.
Concentration of antibody: 1 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (1 mg/ml) in 1X PBS containing 0.02% sodium azide.
Purification method: Affinity chromatography purified via peptide column.
This antibody has been succesfully tested for use in following methods: Western blot, Immunohistochemistry, ELISA
Recommended usage: Western Blot: 0.5-2 μg/ml, Immunohistochemistry: 2.5 μg/ml, ELISA. However, the optimal conditions should be determined individually.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetDRAM
Short name anti-DRAM Antibody (NT)
Technique Antibody, anti
Alternative name antibody to-DRAM (Antibody to) (NT)
Alternative technique antibodies
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anti-DRAM Antibody (NT) | Technique alternative | 0101219329
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