Rabbit Anti Human ERCC2 Antibody-Non-conjugated
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Catalog numberCSB-PA007770ESR2HU_100ul
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PricePlease ask
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Size100ul
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Long nameRabbit Antibody against Human ERCC2, Non-conjugated
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Synonym nameERCC2 Human Antibody
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Species reactivityHuman
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Tested applications recommended dilutionsELISA,WB,IHC;Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
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ConjugationNon-conjugated
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Antibody isotypeIgG
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UniProt IDP18074
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FormatLiquid, diluted in buffer
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Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Purity>95%
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Purification methodAntigen Affinity Purified Antibodies
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Antibody categoryPolyclonal Antibodies
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Immunogen typeRecombinant human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300AA)
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Immunogen speciesHuman
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AliasBasic transcription factor 2 80 kDa subunit,BTF2 p80,CXPD,DNA excision repair protein ERCC-2,DNA repair protein complementing XP-D cells,TFIIH basal transcription factor complex 80 kDa subunit,TFIIH 80 kDa subunit,TFIIH p80,Xeroderma pigmentosum group D-complementing protein,ERCC2,XPD, XPDC
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BackgroundATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
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ClonalityPolyclonal antibody
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Shipping and storageERCC2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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PropertiesIf you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutRabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolERCC2
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Short nameAnti-ERCC2
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Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
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HostRabbit, Rabbits
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SpeciesHuman, Humans
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Alternative nameERCC2 Antibody
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Alternative techniqueantibodies, rabbit-anti
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Alternative to gene targetexcision repair cross-complementing rodent repair deficiency, complementation group 2, COFS2 and EM9 and TFIIH and TTD and XPD, ERCC2 and IDBG-57385 and ENSG00000104884 and 2068, hydrolase activity, nuclei, Ercc2 and IDBG-150400 and ENSMUSG00000030400 and 13871, ERCC2 and IDBG-639452 and ENSBTAG00000002072 and 100125238
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Gene info
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Identity
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Gene
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Long gene nameERCC excision repair 2, TFIIH core complex helicase subunit
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Synonyms gene
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Synonyms gene name
- xeroderma pigmentosum complementary group D
- excision repair cross-complementing rodent repair deficiency, complementation group 2
- excision repair cross-complementation group 2
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Xeroderma pigmentosum complementation groups
- ERCC excision repair associated
- DNA helicases
- General transcription factor IIH complex subunits
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data