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IGF BP5 human recombinant

IGF BP5 human recombinant is available 0 time from Biovision labs

Synonyms insln-like Growth Factor-Binding Protein5
Alternates names insln-like Growth Factor-Binding Protein5
Taglines A protein which binds and prolongs the half-life of the IGFs
Biomolecule/Target NA
NCBI Gene ID #. 3488
NCBI Gene Symbol IBP5
Gene Source Human
Accession # P24593
Recombinant Yes
Source E. coli
Purity ≥98%
Activity (Specifications/test method) N/A
Biological activity The ED₅₀ as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is
Molecular Weight 28. 6 kDa
Storage Temp. -20°C
Shipping Gel pack
Shelf Life 1 year
Concentration N/A
Appearance Lyophilized protein
Physical form description Sterile filtered and lyophilized from 10 mM Sodium Citrate solution, pH 3.0.
Reconstitution Instructions Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description IGF-I, IGF-II, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades.
Additional source Recombinants or rec. proteins
Group recombinants
Gene targetBP5
Short name IGF-BP5, recombinant
Technique Recombinant, IGF
Species Human
Alternative name IGF-BP5, H. sapiens recombinant
Alternative technique rec
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