RAGE, Recombinant, Canine (Receptor for Advanced Glycosylation End Products, Advanced Glycosylation End Product-specific Receptor, AGER)
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Catalog number
MBS637345
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Price
Please ask
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Size
0.05 mg
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Products_type
Active Protein
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Products_short_name
[RAGE, Canine]
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Other_names
[RAGE; advanced glycosylation end product-specific receptor; RAGE/AGER; advanced glycation end product receptor]
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Other_gene_names
[AGER; RAGE]
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Purity
Highly Purified90%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.
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Form
Supplied as a lyophilized powder in PBS. Reconstitute with PBS to 100ug/ml.
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Storage_stability
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile PBS and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Test
Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosylic donor, is attached to a hydroxyl or other functional group of another molecule (a glycosylic acceptor). In biology glycosylation mainly refers in particular to the enzymatic process that attaches glycans to proteins, lipids, or other organic molecules
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
AGER, MOK
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Short name
RAGE, Recombinant, (Receptor for Advanced Glycosylation End Products, Advanced Glycosylation End Product-specific Receptor, AGER)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
Recombinant Canine
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Species
From Canis lupus or the domestic dog we know mostly the Beagle to be used in drug discovery experiments.
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Alternative name
RAGE, Rec., canine (Receptor to measure Advanced Glycosylation End Products, Advanced Glycosylation End reagent-specific Receptor, advanced glycosylation end product-specific receptor)
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Alternative technique
rec
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Alternative to gene target
advanced glycosylation end product-specific receptor, RAGE, AGER and IDBG-80463 and ENSG00000204305 and 177, S100 protein binding, Extracellular, Ager and IDBG-172144 and ENSMUSG00000015452 and 11596, AGER and IDBG-633065 and ENSBTAG00000014420 and 280986
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Gene info
Gene info
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Identity
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Gene
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Long gene name
MOK protein kinase
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Synonyms gene
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1995-05-10
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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