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Immunogen
A phospho-specific peptide corresponding to residues surrounding Thr583 of human CDK11A(AA580-586)
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Antibody s target
Human CDK11A (pThr583)
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Antibody s full description
Rabbit Anti-Human CDK11A (pThr583) Polyclonal
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Antibody s category
Polyclonal Antibodies
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Antibody s other name
CD11A_HUMAN Antibody, CDC2L2 Antibody, CDC2L3 Antibody, CDK11 Antibody, Cell division cycle 2 like 2 (PITSLRE proteins) Antibody, Cell division cycle 2-like protein kinase 2 Antibody, Cell division protein kinase 11A Antibody, Cyclin-dependent kinase 11A Antibody, Galactosyltransferase-associated protein kinase p58/GTA Antibody, p58GTA Antibody, PITSLRE Antibody
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Verified applications
WB, AM
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Raised in
Rabbit
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Antibody s reactivity
Human
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Antibody s recommended dilutions for use
WB (1:250); optimal dilutions for assays should be determined by the user.
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Antibody s purified from
Peptide Affinity Purified
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Recommended buffer for storage
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
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Antibody s concentration
See included datasheet or contact our support service
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Antibody s specificity
Detects 90.974 kDa.
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Storage recommendations
-20°C
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Shipping recommendations
Blue Ice or 4°C
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Certificate of analysis
A 1:250 dilution of SPC-940 was sufficient for detection of CDK11A (pThr583) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Antibody in cell
Cytoplasm, Nucleus
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Tissue specificity
See included datasheet or contact our support service.
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Scientific context
CDK11A is a member of the p34Cdc2 protein-serine/threonine kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. The protein kinase encoded by CDK11A could be cleaved by caspases and was demonstrated to play roles in cell apoptosis.
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Bibliography
Refer to PubMed
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Released date
29/Aug/2016
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NCBI number
NP_055891
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Gene number
728642
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Protein number
Q9UQ88
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Antibody s datasheet
Contact our support service to receive datasheet or other technical documentation.
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Representative figure link
No Data Available
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
1.4
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Net weight g
0.1
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Stock availabilit
In Stock
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Test
StressMark antibodies supplies antibodies that are for research of human proteins.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
RPE, CDK11A
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Short name
Rabbit Anti- CDK11A (pThr583) Polyclonal: RPE
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Technique
anti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Isotype
Immunoglobulin
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Label
RPE
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Species
Human, Humans
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Alternative name
production species: rabbit Antibody toHuman cyclin-dependent phosphorylation catalyst 11A (pThr583) polyclonal: RPE
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Alternative technique
polyclonals, rabbit-anti, antibodies
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Alternative to gene target
cyclin-dependent kinase 11A, CDK11A and IDBG-85824 and ENSG00000008128 and 728642,984, transferase activity, nuclei
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