AG1296,PDGFR kinase inhibitor

• Catalog number
  SIH-426-25MG
• Price
  Please ask
• Size
  25 mg

• Research Area s
  Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
• Category
  Small Molecules
• Product Type
  Inhibitor
• CAS No
  146535-11-7
• MolecularFormula
  C16H14N2O2
• Molecular Weight
  266.3
• Purity
  ≥98% (TLC)
• Solubility
  Soluble in DMSO or dichloromethane
• Appearance
  Off-white to brownish solid
• Storage Temperature
  -20°C
• Shipping Temperature
  Shipped Ambient
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  AG1296   PDGFR   kinase   inhibitor  
• Gene symbol
  PDGFRB
• Short name
  AG1296 PDGFR kinase inhibitor
• Alternative name
  AG1296,PDGFR phosphorylation catalyst suppressor

Gene info

• Identity
  HGNC:8804
• Gene
  PDGFRB
• Long gene name
  platelet derived growth factor receptor beta
• Synonyms gene
  • PDGFR
• Synonyms gene name
  • platelet-derived growth factor receptor, beta polypeptide
• Synonyms
  • JTK12
  • CD140b
  • PDGFR1
• GenBank acession
  • M21616
• Locus
  5q32
• Discovery year
  2001-06-22
• Entrez gene record
  5159
• RefSeq identity
  • NM_002609
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
• VEGA ID
  OTTHUMG00000130053

Similar products