PD184352

• Catalog number
  1585-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  CI-1040
• Description
  A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC₅₀ of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.
• CAS Number
  212631-79-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₄ClF₂IN₂O₂
• Molecular Weight
  478.67
• Cell Permeable
  Yes
• Purity
  ≥99% by HPLC
• Solubilities
  DMSO (600 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  A MEK inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD02683961
• PubChem CID
  6918454
• PubChem CID Link
• SMILES
  C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
• InChi
  InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
• InChi Key
  GFMMXOIFOQCCGU-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PD184352  
• Short name
  PD184352
• Alternative name
  PD184352

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