L-778123 hydrochloride
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Catalog number9638-10
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PricePlease ask
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Size10 mg
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Alternative_name4-((5-((4-(3-chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride
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DescriptionL-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an ICâ‚…â‚€ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.
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CAS Number253863-00-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaCâ‚‚â‚‚Hâ‚‚â‚€ClNâ‚…O
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Molecular Weight405.88
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent FPTase and GGPTase-I inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID216453
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SMILESC1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl
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InChiInChI=1S/C22H20ClN5O.ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;/h1-7,10,12,16H,8-9,13-15H2;1H
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InChi KeyYNBSQYGTJLIPJS-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolCPT1A, POM121L2, L3MBTL2, CLDN10, RPL32P1, FABP1, COX7A2, NFIA, MAS1L, ANP32E
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Short nameL-778123 hydrochloride
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Alternative nameL-778123 hydrochloride
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Gene info
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Identity
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Gene
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Long gene namecarnitine palmitoyltransferase 1A
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Synonyms gene
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Synonyms gene name
- carnitine palmitoyltransferase 1A (liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-05-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePOM121 transmembrane nucleoporin like 2
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Synonyms gene name
- POM121 membrane glycoprotein-like 2 (rat)
- POM121 membrane glycoprotein-like 2
- POM121 transmembrane nucleoporin-like 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-07-20
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameL3MBTL histone methyl-lysine binding protein 2
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Synonyms gene name
- l(3)mbt-like 2 (Drosophila)
- L3MBTL2, polycomb repressive complex 1 subunit
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-04-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MBT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameclaudin 10
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Claudins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameribosomal protein L32 pseudogene 1
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Synonyms gene
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Synonyms gene name
- ribosomal protein L32 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2009-03-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefatty acid binding protein 1
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Synonyms gene name
- fatty acid binding protein 1, liver
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fatty acid binding protein family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecytochrome c oxidase subunit 7A2
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Synonyms gene name
- cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-11-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear factor I A
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Synonyms gene name
- nuclear factor I/A
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-03-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nuclear factor I family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMAS1 proto-oncogene like, G protein-coupled receptor
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Synonyms gene name
- MAS1 oncogene-like
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-11-18
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Entrez gene record
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RefSeq identity
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Classification
- G protein-coupled receptors, Class A orphans
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameacidic nuclear phosphoprotein 32 family member E
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Synonyms gene name
- acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-04-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ANP32 acidic nuclear phosphoproteins
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VEGA ID