DPP4 Activity Fluorometric Assay Kit

  • Catalog number
    K779-100
  • Price
    Please ask
  • Size
    100 assays
  • Description
    Highly Sensitive Assay, HTS
  • Summary
    • Detection method- Fluorescence (Ex/Em 360/460 nm) • Species reactivity- Mammalian • Applications- This kit detects DPP4 activity as low as 3 µU per well.
  • Sample Type
    Cell and tissue culture lysates, plasma, serum, other biological fluids, cell culture medium, etc.
  • Storage Conditions
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf life
    12 months
  • Background
    Dipeptidyl peptidase-4 (DPP4), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein that, in humans, is encoded by the DPP4 gene. The substrates of CD26/DPP4 are proline (or alanine) containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPP4 plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1 and hence its inhibition by drugs such as Sitagliptin have been used for treatment of diabetes mellitus type 2. DPP4 also appears to work as a suppressor in the development of cancer and tumors. In BioVision’s DPP4 Activity Assay Kit, DPP4 cleaves a substrate to release a quenched fluorescent group, AMC (7-Amino-4-Methyl Coumarin), (Ex/Em = 360/460 nm). This assay is rapid, simple, sensitive, and reliable, as well as, suitable for high throughput activity screening of DPP4. This kit detects DPP4 activity as low as 3 µU per well.
  • Test
    Biovision supplies other types of Assays as 1.
  • Gene target
  • Gene symbol
    DPP4-DT, DPP4
  • Short name
    DPP4 Activity Fluorometric Assay Kit
  • Technique
    Assay, assays
  • Host
    Assay
  • Alternative name
    dipeptidyl-peptidase 4 Activity fluorescence test reagent
  • Alternative technique
    arrays, kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
Gene info
  • Identity
  • Gene
  • Long gene name
    DPP4 divergent transcript
  • Locus
  • Discovery year
    2019-07-25
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Divergent transcripts
Gene info
  • Identity
  • Gene
  • Long gene name
    dipeptidyl peptidase 4
  • Synonyms gene
  • Synonyms gene name
    • dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
    • adenosine deaminase complexing protein 2
    • dipeptidyl-peptidase 4
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1990-03-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • CD molecules
    • DASH family
  • VEGA ID
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