DPP4 Activity Fluorometric Assay Kit
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Catalog number
K779-100
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Price
Please ask
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Size
100 assays
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Description
Highly Sensitive Assay, HTS
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Summary
• Detection method- Fluorescence (Ex/Em 360/460 nm) • Species reactivity- Mammalian • Applications- This kit detects DPP4 activity as low as 3 µU per well.
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Sample Type
Cell and tissue culture lysates, plasma, serum, other biological fluids, cell culture medium, etc.
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Storage Conditions
-20°C
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Shipping Conditions
gel pack
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Shelf life
12 months
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Background
Dipeptidyl peptidase-4 (DPP4), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein that, in humans, is encoded by the DPP4 gene. The substrates of CD26/DPP4 are proline (or alanine) containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPP4 plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1 and hence its inhibition by drugs such as Sitagliptin have been used for treatment of diabetes mellitus type 2. DPP4 also appears to work as a suppressor in the development of cancer and tumors. In BioVision’s DPP4 Activity Assay Kit, DPP4 cleaves a substrate to release a quenched fluorescent group, AMC (7-Amino-4-Methyl Coumarin), (Ex/Em = 360/460 nm). This assay is rapid, simple, sensitive, and reliable, as well as, suitable for high throughput activity screening of DPP4. This kit detects DPP4 activity as low as 3 µU per well.
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Test
Biovision supplies other types of Assays as 1.
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Gene target
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Gene symbol
DPP4-DT, DPP4
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Short name
DPP4 Activity Fluorometric Assay Kit
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Technique
Assay, assays
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Host
Assay
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Alternative name
dipeptidyl-peptidase 4 Activity fluorescence test reagent
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Alternative technique
arrays, kits
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Alternative to gene target
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
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Gene info
Gene info
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Identity
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Gene
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Long gene name
dipeptidyl peptidase 4
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Synonyms gene
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Synonyms gene name
- dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
- adenosine deaminase complexing protein 2
- dipeptidyl-peptidase 4
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Synonyms
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GenBank acession
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Locus
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Discovery year
1990-03-05
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Product images
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