HPV16-E7 Antibody
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Catalog numberbs-10446R
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PricePlease ask
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Size0.1ml
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Long nameHPV16-E7 Primary Polyclonal Antibody
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Also known asHPV16-E7 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenHPV16-E7
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SpecificityThis is a highly specific antibody against HPV16-E7. This antibody may also detect HPV35-E7
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range50-98/98
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SourceKLH conjugated synthetic peptide derived from middle of HPV16-E7
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Gene ID number1489079
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Swiss ProtP03129
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityVirus
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Cross reactive species detailsHPV16
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Background of the target antigenPlays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesProtein E7; E7
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Short nameAnti-HPV16-E7
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameHPV16-E7 Polyclonal Antibody
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Alternative techniqueantibodies
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MeSH Data
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Name
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ConceptScope note: Methods for detecting or typing the DNA of an ALPHAPAPILLOMAVIRUS in biological tissues and fluids.
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Tree numbers
- E01.370.225.880.500
- E05.200.880.500
- E05.393.520.750
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data