Complement C3 beta chain Antibody, ALEXA FLUOR 350

  • Catalog number
    bs-4871R-A350
  • Price
    Please ask
  • Size
    100ul
  • Long name
    Complement C3 beta chain Antibody, ALEXA FLUOR 350 Conjugated
  • Also known as
    Anti-Complement C3 beta chain PAb ALEXA FLUOR 350
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 350
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Complement C3 beta chain
  • Specificity
    This is a highly specific antibody against Complement C3 beta chain.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen range
    585-635/1663
  • Subcellular location
    Secreted
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement C3 beta chain
  • Gene ID Number
    718
  • Swiss Prot
    P01024
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity). It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2 (PubMed:8376604, PubMed:2909530, PubMed:9059512, PubMed:10432298, PubMed:15833747, PubMed:16333141, PubMed:19615750).
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    343nm/442nm
  • Synonyms
    ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 350
  • French translation
    anticorps
  • Gene target
    Complement   beta   chain  
  • Short name
    Anti-Complement C3 beta chain
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 350
  • Alternative name
    Complement C3 beta chain Antibody, ALEXA FLUOR 350
  • Alternative technique
    antibodies
  • Alternative to gene target
    complement component 3, AHUS5 and ARMD9 and ASP and C3a and C3b and CPAMD1 and HEL-S-62p, C3 and IDBG-21798 and ENSG00000125730 and 718, C5L2 anaphylatoxin chemotactic receptor binding, Extracellular, C3 and IDBG-193788 and ENSMUSG00000024164 and 102642251,12266, BT.19562 and IDBG-643930 and ENSBTAG00000017280 and 280677
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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