Human Leukemia inhibitory factor receptor ?? (LIFR) CRISPR Knock Out U87-MG Cell Line

• Catalog number
  K0009059
• Price
  Please ask
• Size
  1x10^6 cells/1.0ml

• Cell line type
  U87-MG
• NCBI number
  NM_001127671/NM_002310
• Availability
  Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
• Ordering
  If you wish to order this product, please include the catalogue number #K0009059in your purchase order among with your shipping and billing information.
• Technical file
  Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
• Notes
  Designed for Research Use Only. Manufactured in Canada.
• Other products
• Description
  For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Leukemia   inhibitory   factor   receptor   LIFR   CRISPR   Knock   Out   U87-MG   Line  
• Gene symbol
  LIFR-AS1, LIFR, SCARNA5, SNORD87, GLG1
• Short name
  Leukemia inhibitory factor receptor ?? (LIFR) CRISPR Knock Out U87-MG Line
• Species
  Human, Humans
• Alternative name
  H. sapiens Leukemia inhibitory factor receptor ?? (leukemia inhibitory factor receptor alpha) CRISPR Knock Out U87-MG cellular Line
• Alternative to gene target
  leukemia inhibitory factor receptor alpha, CD118 and LIF-R and SJS2 and STWS and SWS, LIFR and IDBG-17489 and ENSG00000113594 and 3977, growth factor binding, Extracellular, Lifr and IDBG-128297 and ENSMUSG00000054263 and 16880, LIFR and IDBG-630017 and ENSBTAG00000010423 and 539504
• Tissue
  cell
• Virus
  leukemia

Gene info

• Identity
  HGNC:43600
• Gene
  LIFR-AS1
• Long gene name
  LIFR antisense RNA 1
• Synonyms gene name
  • LIFR antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC038371
• Locus
  5p13.1
• Discovery year
  2011-11-23
• Entrez gene record
  100506495
• Pubmed identfication
  • 26725846
  • 29807108
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000162109

Gene info

• Identity
  HGNC:6597
• Gene
  LIFR
• Long gene name
  LIF receptor subunit alpha
• Synonyms gene name
  • leukemia inhibitory factor receptor
  • leukemia inhibitory factor receptor alpha
  • LIF receptor alpha
• Synonyms
  • CD118
• GenBank acession
  • X61615
• Locus
  5p13.1
• Discovery year
  1992-08-24
• Entrez gene record
  3977
• Pubmed identfication
  • 1915266
• RefSeq identity
  • NM_002310
• Classification
  • Fibronectin type III domain containing
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000131138

Gene info

• Identity
  HGNC:32561
• Gene
  SCARNA5
• Long gene name
  small Cajal body-specific RNA 5
• Synonyms
  • U87
• GenBank acession
  • AY077737
• Locus
  2q37.1
• Discovery year
  2006-03-31
• Entrez gene record
  677775
• Pubmed identfication
  • 12032087
• RefSeq identity
  • NR_003008
• Classification
  • Small Cajal body-specific RNAs

Gene info

• Identity
  HGNC:32746
• Gene
  SNORD87
• Long gene name
  small nucleolar RNA, C/D box 87
• Synonyms
  • HBII-276
  • U87
• Locus
  8q13.1
• Discovery year
  2006-05-08
• Entrez gene record
  641648
• Pubmed identfication
  • 12119114
  • 11387227
• RefSeq identity
  • NR_002598
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:4316
• Gene
  GLG1
• Long gene name
  golgi glycoprotein 1
• Synonyms gene name
  • golgi apparatus protein 1
• Synonyms
  • MG-160
  • ESL-1
  • CFR-1
• Locus
  16q23.1
• Discovery year
  1995-09-11
• Entrez gene record
  2734
• Pubmed identfication
  • 8530051
  • 7531823
• RefSeq identity
  • NM_012201
• VEGA ID
  OTTHUMG00000177174

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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