Thrombospondin, human recombinant

  • Catalog number
    4805-1000
  • Price
    Please ask
  • Size
    1 mg
  • Synonyms
    Thrombospondin-1, THBS1, TSP, TSP1, THBS, THBS-1
  • Alternative_names
    Thrombospondin-1, THBS1, TSP, TSP1, THBS, THBS-1
  • Description
    A secreted protein with antiangiogenic abilities
  • Recombinant
    Yes
  • Source
    Baculovirus (Sf9 insect cells)
  • Purity by SDS PAGE
    ≥98%
  • Assay
    SDS-PAGE
  • Purity
    ≥98%
  • Molecular Weight
    181 kDa in reducing gel
  • Storage Temp
    -20°C
  • Shipping
    Blue ice
  • Shelf Life
    12 months
  • Appearance
    Lyophilized protein
  • Physical form description
    Lyophilized from 20 mM sodium phosphate, pH 6.0, 300 mM NaCl and 0.1% BSA.
  • Reconstitution Instructions
    Reconstitute with water at the concentration 0.1 mg/ml.
  • Background Information
    Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been used as a potential regulator of tumor growth and metastasis. TSP expression is highly regulated by different hormones and cytokines and is developmentally controlled. TSP stimulates the growth of Vascular smooth muscle cells and human foreskin fibroblasts, a combination of IFN-γ and TNF-α inhibits TSP production in these cells. Recombinant Human Thrombospondin is glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. Human Thrombospondin is purified by proprietary chromatographic techniques.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    THBS1, THBS3, THSD1
  • Short name
    Thrombospondin, recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Thrombospondin, H. sapiens Rec.
  • Alternative technique
    rec
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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