BAY-1895344 hydrochloride

  • Catalog number
    B1962-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine hydrochloride
  • Description
    BAY-1895344, an orally available, potent ATR (ataxia telangiectasia and Rad3-related) protein inhibitor (IC₅₀ = 7 nM). Displays potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride.
  • CAS Number
    1876467-74-1 (free base)
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₀H₂₂ClN₇O
  • Molecular Weight
    411.89
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent ATR (ataxia telangiectasia and Rad3-related) protein inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    118869362
  • SMILES
    CC1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5=CC=NN5C
  • InChi
    InChI=1S/C20H21N7O/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6-21-20(19(14)24-18)16-4-7-22-25-16/h3-8,11,13H,9-10,12H2,1-2H3,(H,22,25)/t13-/m1/s1
  • InChi Key
    YBXRSCXGRPSTMW-CYBMUJFWSA-N
  • MSDS Available
    Yes
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