Human CellExp™ CNDP1, Human recombinant

• Catalog number
  P1125-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  CNDP1, CN1, CPGL2
• Alternative_names
  CNDP1, CN1, CPGL2
• Recombinant
  Yes
• Source
  HEK 293 cells
• Purity by SDS PAGE
  > 95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Molecular Weight
  54.7 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute in sterile deionized water to the desired protein concentration.
• Background Information
  Beta-Ala-His dipeptidase is also known as Carnosine dipeptidase 1 (CNDP1), CNDP dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase, CPGL2, which belongs to the peptidase M20A family. CNDP1 is found in serum and adult nervous central system. CNDP1 preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine), and also anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine. The catalytic activity of CNDP1 is inhibited by the metal chelator 1,10-o-phenantrolin and the inhibitory concentration 50% (IC50) is 5 µM.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   CNDP1  
• Gene symbol
  CNDP1
• Short name
  CellExp™ CNDP1, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ CNDP1, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:20675
• Gene
  CNDP1
• Long gene name
  carnosine dipeptidase 1
• Synonyms gene name
  • carnosine dipeptidase 1 (metallopeptidase M20 family)
• Synonyms
  • MGC10825
  • CN1
  • CPGL2
  • HsT2308
• Synonyms name
  • carnosinase 1
  • glutamate carboxypeptidase-like protein 2
  • beta-Ala-His dipeptidase
• Locus
  18q22.3
• Discovery year
  2004-04-14
• Entrez gene record
  84735
• Pubmed identfication
  • 12473676
• RefSeq identity
  • NM_032649
• Classification
  • M20 metallopeptidases
• VEGA ID
  OTTHUMG00000132852

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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