anti-CX3CL1 Antibody
-
Catalog number2099
-
PricePlease ask
-
Size0.02 mg, 0.1 mg
-
-
Gene infoCX3CL1 Antibody: Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a; in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.
-
Gene namesCX3CL1 Antibody: NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin, FKN, A-152E5.2, Fractalkine, C-X3-C motif chemokine 1
-
Antibodie s labelunlabelled serum
-
PurityCX3CL1 Antibody is affinity chromatography purified via peptide column.
-
Ab raised inRabbit
-
TypePolyclonal
-
ImmunoglobulinIgG
-
AntigenCX3CL1 antibody was made against a peptide corresponding to 18 amino acids near the amino terminus of human CX3CL1.
-
Immuno applicationELISA, Western Blot, immuno precipitation
-
Antibody adviceCX3CL1 antibody can be used for detection of CX3CL1 by Western blot at 0.5 - 2 mg/mL dilution. CX3CL1 is ofen observed migrating at 80 - 100 kDa in SDS-PAGE, presumably due to post-translational modification.
-
Suspention pH azideCX3CL1 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep atCX3CL1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works withHuman, Mouse
-
Omim nr1899259
-
Ncbi nrAAB50014
-
Vial with antibodyin solution
-
NCBI GENE nr6376
-
GENE symbolCX3CL1
-
Antigene namechemokine (C-X3-C motif) ligand 1
-
SourceHomo sapiens
-
Protein nrP78423
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCX3CL1
-
Short nameanti-CX3CL1 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody tochemokine (C-X3-C motif) ligand 1 (antibody to-)
-
Alternative techniqueantibodies
-
Alternative to gene targetchemokine (C-X3-C motif) ligand 1, ABCD-3 and C3Xkine and CXC3 and CXC3C and fractalkine and neurotactin and NTN and NTT and SCYD1, CX3CL1 and IDBG-33205 and ENSG00000006210 and 6376, chemokine activity, Extracellular, Cx3cl1 and IDBG-182616 and ENSMUSG00000031778 and 20312, CX3CL1 and IDBG-632469 and ENSBTAG00000024869 and
-
Gene info
-
Identity
-
Gene
-
Long gene nameC-X3-C motif chemokine ligand 1
-
Synonyms gene
-
Synonyms gene name
- small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
- chemokine (C-X3-C motif) ligand 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1997-08-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Chemokine ligands
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data