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anti-NDRG1 Antibody

anti-NDRG1 Antibody is available 1 time from Biovision labs

3526-100 | anti-NDRG1 Antibody size: NDRG1 Antibody | 423.90 USD

Catalog number 3526-100
Supplier Biovision
Price 423.90 USD
Size NDRG1 Antibody
1. Gene info
Identity 7679
Gene NDRG1
Long gene name N-myc downstream regulated 1
Synonyms gene
  • CAP43
Synonyms
  • DRG1
  • RTP
  • TDD5
  • NDR1
GenBank acession
  • X92845
Locus 8q24.22
Discovery year 1998-12-23
Entrez gene record 10397
Pubmed identfication
  • 9251681
  • 8939898
  • 18455888
Classification
  • NDRG family
Havana BLAST/BLAT OTTHUMG00000164441
Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_258
Product images
    #0#.jpeg
Target of this antibody: NDRG1
Alternative names of antibody target: N-myc downstream regulated 1, CAP43, CMT4D, DRG1, GC4, HMSNL, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5
Background information: NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is one of 4 members of the NDRG α/β-hydrolase family. It is classified as a tumor suppressor and heavy metal-response protein. NDRG1’s functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. It is also essential for p53-mediated caspase activation and apoptosis. NDRG1 is ubiquitous; it is expressed most notably in placental membranes and prostate, kidney, small intestine, and ovary tissues. NDRG1 has reduced expression in adenocarcinomas compared to normal tissues. NDRG1 gene mutations are reported to be the cause for hereditary motor and sensory neuropathy-Lom (HMSNL), which is a severe autosomal recessive form of Charcot- Marie-Tooth (CMT) disease. In addition, decreased NDRG1 expression in glioma is linked to tumor progression. On the other hand, overexpression of NDRG1 is connected to malignant status of esophageal cancer. NDRG1 may also have a role in portal vein invasion and intrahepatic metastasis in human hepatocellular carcinoma.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse, rat
Immunogene sequence: Synthetic peptide at C-terminal
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blot: 1:200
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetNDRG1
Short name anti-NDRG1 Antibody
Technique Antibody, anti
Alternative name antibody to-N-v-myc myelocytomatosis viral oncogene homolog (avian) downstream regulated 1 (Antibody to)
Alternative technique antibodies
Alternative to gene target N-myc downstream regulated 1, CAP43 and CMT4D and DRG-1 and DRG1 and GC4 and HMSNL and NDR1 and NMSL and PROXY1 and RIT42 and RTP and TARG1 and TDD5, NDRG1 and IDBG-36420 and ENSG00000104419 and 10397, cadherin binding, nuclei, Ndrg1 and IDBG-146853 and ENSMUSG00000005125 and 17988, NDRG1 and IDBG-644056 and ENSBTAG00000000711 and 504499
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anti-NDRG1 Antibody | Technique alternative | 01012192444
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