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anti-MCM2 Antibody

anti-MCM2 Antibody is available 1 time from Biovision labs

3758-100 | anti-MCM2 Antibody size: MCM2 Antibody | 374.93 USD

Catalog number 3758-100
Supplier Biovision
Price 374.93 USD
Size MCM2 Antibody
1. Gene info
Identity 6950
Gene MCM7
Long gene name minichromosome maintenance complex component 7
Synonyms gene
  • MCM2
Synonyms gene name
  • minichromosome maintenance deficient (S. cerevisiae) 7
  • MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
Synonyms
  • CDC47
  • PPP1R104
Synonyms name
  • protein phosphatase 1, regulatory subunit 104
Locus 7q22.1
Discovery year 1994-12-13
Entrez gene record 4176
Pubmed identfication
  • 7842741
Classification
  • MCM family
  • minichromosome maintenance 2-7 complex
  • Protein phosphatase 1 regulatory subunits
  • MicroRNA protein coding host genes
Havana BLAST/BLAT OTTHUMG00000154671
2. Gene info
Identity 6944
Gene MCM2
Long gene name minichromosome maintenance complex component 2
Synonyms gene
  • CCNL1
  • CDCL1
Synonyms gene name
  • minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin)
  • MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
Synonyms
  • D3S3194
  • KIAA0030
  • BM28
  • cdc19
  • DFNA70
Synonyms name
  • mitotin
GenBank acession
  • X67334
Locus 3q21.3
Discovery year 1993-09-30
Entrez gene record 4171
Pubmed identfication
  • 1710453
  • 8258304
  • 26196677
Classification
  • MCM family
  • minichromosome maintenance 2-7 complex
Havana BLAST/BLAT OTTHUMG00000159637
Product images
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Target of this antibody: MCM2
Alternative names of antibody target: Mitotin; BM28, Nuclear protein BM28; cdc19; CCNL1, cyclin like-1; CDCL1, CDC like-1; D3S3194; KIAA0030
Background information: The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1 to S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the postreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro. Cleavage of MCM3, which can be prevented by caspase inhibitors, results in the inactivation during apoptosis of the MCM complex, which is composed of, at least, MCM2–6. A complex composed of MCM4, MCM6 and MCM7 has been shown to be involved in DNA helicase activity, and MCM5 is involved in IFN-©-induced Stat1å transcription activation.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse
Immunogene sequence: Synthetic peptide of human MCM2
Concentration of antibody: N/A
Form of antibody: Liquid
Formulation of this antibody: 100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot, Immunoprecipitation
Recommended usage: Western blotting (1:500 – 1:2500) and Immunoprecipitation. HeLa cell extract can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the MCM2 of human origin. Reactivity to mouse is expected due to sequence homology. Reactivity to other species has not been tested.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetMCM2
Short name anti-MCM2 Antibody
Technique Antibody, anti
Alternative name antibody to-MCM2 (Antibody to)
Alternative technique antibodies
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anti-MCM2 Antibody | Technique alternative | 01012192844
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