Human CellExp™ Influenza A [A/Hong Kong/483/97(H5N1)] Hemagglutinin (HA), Recombinant
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Catalog number
P1005-20
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Price
Please ask
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Size
20 ug
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Synonyms
N/A
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Alternative_names
N/A
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Description
A major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin is responsible for penetration of the virus
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Recombinant
Yes
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Source
HEK 293 cells
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Molecular Weight
This protein is fused with polyhistidine tag at the C-terminus, has a predicted MW of 53.8 kDa. The protein migrates to 80-110 kDa due to glycosylation.
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Storage Temp
-20°C
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Shipping
Gel pack
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Shelf Life
12 months
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Appearance
Dry powder
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Physical form description
Lyophilized powder
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Reconstitution Instructions
Reconstitute in sterile deionized water to a stock solution of 100 µg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% (W/V) HSA or BSA) is recommended for further dilution and long term storage.
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Background Information
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
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Amino acid sequence
Asp 17 - Gln 531
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional description
Influenza A and B H1N1 H3N2 Hemagglutinin-nucleoprotein recombinant proteins, peptides and antibodies detect a virus commonly known as "the flu". Influenza is an infectious disease caused by an influenza virus. Symptoms can be mild to severe. The most common symptoms include a high fever, runny nose, sore throat, muscle pains, headache, coughing, and feeling tired. These symptoms typically begin two days after exposure to the virus and most last less than a week. The cough, however, may last for more than two weeks. In children, there may be nausea and vomiting, but these are not common in adults.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Short name
CellExp™ Influenza A [A/Hong Kong/483/97(H5N1)] Hemagglutinin (HA), Recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Humans, Influenza
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Alternative name
H. sapiens CellExp™ Influenza A [A/Hong Kong/483/97(H5N1)] Hemagglutinin (HA), Rec.
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Alternative technique
rec
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Virus
influenza
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MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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