anti-APC4 Antibody
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Catalog number5725
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoAPC4 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC4 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC4, it is thought that APC4 associates with other APC/C components APC1, APC5, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.
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Gene namesAPC4 Antibody: APC4, APC4, Anaphase-promoting complex subunit 4, Cyclosome subunit 4
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Antibodie s labelunlabelled serum
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PurityAPC4 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenAPC4 antibody was made against a 14 amino acid synthetic peptide near the amino terminus of human APC4.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceAPC4 antibody can be used for detection of APC4 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azideAPC4 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atAPC4 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr205371737
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Ncbi nrQ9UJX5
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr29945
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GENE symbolANAPC4
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Antigene nameanaphase promoting complex subunit 4
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SourceHomo sapiens
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Protein nrQ9UJX5
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolANAPC4, SLC25A41
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Short nameanti-APC4 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toAPC4 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameanaphase promoting complex subunit 4
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Anaphase promoting complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 25 member 41
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Synonyms gene name
- solute carrier family 25, member 41
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-09-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
