MDC/CCL22, murine recombinant

  • Catalog number
    7169-50
  • Price
    Please ask
  • Size
    50 ug
  • Synonyms
    Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1
  • Alternative_names
    Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1
  • Description
    Chemoattracts monocytes, dendritic cells and NK cells
  • Recombinant
    Yes
  • Source
    E. Coli
  • Purity by SDS PAGE
    ≥98%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    < 0.1 ng/ug of protein (
  • Activity Specifications test method
    Determined by its ability to chemoattract human activated lymphocytes using a concentration range of 10.0-100.0 ng/ml.
  • Biological activity
    Determined by its ability to chemoattract human activated lymphocytes using a concentration range of 10.0-100.0 ng/ml.
  • Molecular Weight
    7.8 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized powder
  • Physical form description
    Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
  • Reconstitution Instructions
    Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
  • Background Information
    MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
  • Amino acid sequence
    GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    ADAM11, CCL22, ADAM28, TNFAIP8
  • Short name
    MDC/CCL22, murine recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    MDC/chemokine (C-C motif) ligand 22, murine Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    chemokine (C-C motif) ligand 22, ABCD-1 and DC/B-CK and MDC and SCYA22 and STCP-1, CCL22 and IDBG-33170 and ENSG00000102962 and 6367, chemokine activity, Extracellular, Ccl22 and IDBG-182591 and ENSMUSG00000031779 and 20299, CCL22 and IDBG-632465 and ENSBTAG00000017718 and 616996
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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