Gbx2 Antibody, HRP Conjugated

• Catalog number
  bs-11849R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  Gbx2 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Gbx2
• Specificity
  This is a highly specific antibody against Gbx2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human Gbx2
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes Gbx2 and Otx2. Gbx2 and Otx2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, Gbx2 negatively regulates Otx2 expression along the anterior-posterior axis; Gbx2(-) mutants demonstrate an expanded Otx2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. Gbx2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is over-expressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of Gbx2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that Gbx2 expression may be required for growth of malignant prostate cells.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Gastrulation and brain-specic homeobox protein 2; Gastrulation brain homeo box 2 ; Gastrulation brain homeo box 2; gbx2; GBX2_HUMAN; Homeobox protein GBX 2 ; Homeobox protein GBX 2; Homeobox protein GBX-2; Homeobox protein STRA7; Mmoxa.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  Gbx2   Conjugated  
• Short name
  Anti-Gbx2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-Gbx2 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  gastrulation brain homeobox 2, GBX2 and IDBG-84062 and ENSG00000168505 and 2637, sequence-specific DNA binding, nuclei, Gbx2 and IDBG-179809 and ENSMUSG00000034486 and 14472, BT.106426 and IDBG-642010 and ENSBTAG00000008898 and 507344

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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