Eotaxin Antibody / CCL11

• Catalog number
  R32127
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Eotaxin / CCL11
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,ELISA : 0.1-0.5ug/ml
• Notes
  Optimal dilution of the CCL11 antibody should be determined by the researcher.
• Intented use
  This CCL11 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P51671
• Purity
  Antigen affinity
• Description
  CCL11 (Chemokine (C-C motif) ligand 11), also known as Eotaxin, is a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxin is a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
• Immunogen
  Amino acids 24-97 of human Eotaxin/CCL11 were used as the immunogen for the CCL11 antibody.
• Storage
  After reconstitution, the CCL11 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Eotaxin   CCL11  
• Gene symbol
  CCL11
• Short name
  Anti-Eotaxin / CCL11
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Eotaxin / CCL11
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) ligand 11, SCYA11, CCL11 and IDBG-40645 and ENSG00000172156 and 6356, chemokine activity, Extracellular, Ccl11 and IDBG-204519 and ENSMUSG00000020676 and 20292, CCL11 and IDBG-630948 and ENSBTAG00000004129 and 404072

Gene info

• Identity
  HGNC:10610
• Gene
  CCL11
• Long gene name
  C-C motif chemokine ligand 11
• Synonyms gene
  • SCYA11
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
  • chemokine (C-C motif) ligand 11
• Synonyms
  • eotaxin
  • MGC22554
• Synonyms name
  • eotaxin-1
• GenBank acession
  • AB063614
• Locus
  17q12
• Discovery year
  1996-04-24
• Entrez gene record
  6356
• Pubmed identfication
  • 9169149
• RefSeq identity
  • NM_002986
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132884

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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