Eotaxin Antibody

• Catalog number
  R30607
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Eotaxin
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Eotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Eotaxin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P48298
• Purity
  Antigen affinity
• Description
  Eotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
• Immunogen
  An amino acid sequence from the C-terminus of mouse Eotaxin (CADPKKKWVQDATKHLDQKLQ) was used as the immunogen for this Eotaxin antibody (100% rat homology).
• Storage
  After reconstitution, the Eotaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Eotaxin  
• Gene symbol
  CCL11, CCL24, CCL26
• Short name
  Anti-Eotaxin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Eotaxin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10610
• Gene
  CCL11
• Long gene name
  C-C motif chemokine ligand 11
• Synonyms gene
  • SCYA11
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
  • chemokine (C-C motif) ligand 11
• Synonyms
  • eotaxin
  • MGC22554
• Synonyms name
  • eotaxin-1
• GenBank acession
  • AB063614
• Locus
  17q12
• Discovery year
  1996-04-24
• Entrez gene record
  6356
• Pubmed identfication
  • 9169149
• RefSeq identity
  • NM_002986
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132884

Gene info

• Identity
  HGNC:10623
• Gene
  CCL24
• Long gene name
  C-C motif chemokine ligand 24
• Synonyms gene
  • SCYA24
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 24
  • chemokine (C-C motif) ligand 24
• Synonyms
  • Ckb-6
  • MPIF-2
  • eotaxin-2
  • MPIF2
• Synonyms name
  • CK-beta-6
  • myeloid progenitor inhibitory factor 2
  • eotaxin-2
• GenBank acession
  • U85768
• Locus
  7q11.23
• Discovery year
  1997-11-14
• Entrez gene record
  6369
• Pubmed identfication
  • 9104803
  • 9598329
• RefSeq identity
  • NM_002991
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000156635

Gene info

• Identity
  HGNC:10625
• Gene
  CCL26
• Long gene name
  C-C motif chemokine ligand 26
• Synonyms gene
  • SCYA26
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 26
  • chemokine (C-C motif) ligand 26
• Synonyms
  • MIP-4alpha
  • eotaxin-3
  • IMAC
  • MIP-4a
  • TSC-1
• Synonyms name
  • macrophage inflammatory protein 4-alpha
  • small inducible cytokine A26
  • CC chemokine IMAC
  • chemokine N1
  • thymic stroma chemokine-1
  • eotaxin-3
• GenBank acession
  • AF124601
• Locus
  7q11.23
• Discovery year
  1999-06-09
• Entrez gene record
  10344
• Pubmed identfication
  • 10373330
• RefSeq identity
  • NM_006072
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000130403

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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