CD86 Antibody
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Catalog numberGEN438023
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PricePlease ask
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Size100ug
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Also known asCD86
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Other namesT-lymphocyte activation antigen CD86 isoform 4; T-lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 molecule; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD_antigen: CD86
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameCD86
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Gene name synonimsN/A
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Other gene namesCD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1, kappa
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CloneBU63
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearanceN/A
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ConcentrationN/A
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Storage and shippingStore the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applicationsFlow Cytometry (FC/FACS)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCD86
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Short nameCD86 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameAnti-CD86
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Alternative techniqueantibodies
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Alternative to gene targetCD86 molecule, B7-2 and B7.2 and B70 and CD28LG2 and LAB72, CD86 and IDBG-52336 and ENSG00000114013 and 942, coreceptor activity, Cell surfaces, Cd86 and IDBG-158071 and ENSMUSG00000022901 and 12524, CD86 and IDBG-633264 and ENSBTAG00000013118 and 414345
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Gene info
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Identity
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Gene
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Long gene nameCD86 molecule
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Synonyms gene
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Synonyms gene name
- CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-12-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- B7 family
- CD molecules
- V-set domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data