BCTC, TRPV1 blocker

• Catalog number
  SIH-307-10MG
• Price
  Please ask
• Size
  10 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  393514-24-4
• Description
  TRPV1 blocker
• Molecular weight
  372,89 g/mol
• Primary research fields
  Neuroscience, Ion Channels, Transient Receptor Potential Channels
• Other name
  4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide
• Product category
  Small Molecules
• Product type
  Inhibitor
• Chemical formula
  C20H25ClN4O
• Origin
  Synthetic
• Purity pourcentage
  >98%
• Soluble in
  Soluble to 100 mM in DMSO and to 40 mM in ethanol
• Physical appearance
  White Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
• PubChem number
  9929425
• Scientific context
  BCTC is an inhibitor of capsaicin- and acid-mediated currents at rat VR1. Thus it has effects on acute, inflammatory and neuropathic pain in rats (1, 2).
• Bibliography
  1. Pomonis J.D., et al. (2003) J Pharmacol Exp Ther. 306(1): 387-393. 2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386.
• Release date
  8-Apr-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of BCTC (SIH-307), a TRPV1 blocker. CAS #: 393514-24-4. Molecular Formula: C20H25ClN4O. Molecular Weight: 372.89 g/mol. Chemical structure of BCTC, a TRPV1 blocker (SIH-307). CAS # 393514-24-4. Molecular Formula: C20H25ClN4O.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.01
• Other related products

• Gene target
  BCTC   TRPV1   blocker  
• Gene symbol
  TRPV1
• Short name
  BCTC, TRPV1 blocker
• Alternative name
  BCTC, TRPV1 blocker

Gene info

• Identity
  HGNC:12716
• Gene
  TRPV1
• Long gene name
  transient receptor potential cation channel subfamily V member 1
• Synonyms gene
  • VR1
• Synonyms gene name
  • vanilloid receptor subtype 1
  • transient receptor potential cation channel, subfamily V, member 1
• GenBank acession
  • AJ272063
• Locus
  17p13.2
• Discovery year
  1997-12-05
• Entrez gene record
  7442
• Pubmed identfication
  • 9349813
  • 11549313
  • 16382100
• RefSeq identity
  • NM_018727
• Classification
  • Ankyrin repeat domain containing
  • Transient receptor potential cation channels
• VEGA ID
  OTTHUMG00000177649

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