Annexin V, human recombinant

• Catalog number
  1005-5000
• Price
  Please ask
• Size
  5 mg

• Synonyms
  Annexin V, human recombinant
• Alternative_names
  Anchorin CII, Annexin V, Annexin-5, Calphobindin I, Endonexin II, Lipocortin V, Placental anticoagulant protein 4, lacental anticoagulant protein I, Thromboplastin inhibitor, Vascular anticoagulant-alpha, PP4, ANX5, ENX2, ANXA5, Annexin A5, Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, CBP-I, Placental anticoagulant protein I, PAP-I, Placental anticoagulant protein 4, VAC-alpha, Anchorin CII.
• Description
  A reagent for detecting early stages of apoptosis
• Recombinant
  Yes
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Storage Temp
  +4°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Concentration
  1 mg/ml
• Appearance
  Liquid
• Physical form description
  Liquid form (1 mg/ml in PBS, pH 7.4)
• Reconstitution Instructions
  Reconstitute the lyophilized forms with H₂O or PBS to a final concentration of 1-5 mg/ml.
• Background Information
  Reagent for detecting early stages of apoptosis. During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. The unlabeled Annexin V reagent can be conjugated to any tag of choice for detection of apoptosis. The reagent can also be used in competition binding experiments to compete with tagged annexin V conjugates. Annexin V-FITC, -Cy3, -Cy5, -EGFP, -PE, PE/CY5, and -Biotin Labels are also available separately.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional description
  This Annexin V calcium dependent phospholipid binding protein will be downstream of BCL2 pathway and at caspase apoptotic level. Biovision has more cell death kits and antibodies.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Annexin  
• Gene symbol
  ANXA5
• Short name
  Annexin V, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Annexin V, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:543
• Gene
  ANXA5
• Long gene name
  annexin A5
• Synonyms gene
  • ENX2
  • ANX5
• Synonyms
  • CPB-I
  • PAP-I
  • VAC-alph
  • RPRGL3
• Synonyms name
  • annexin V
  • Calphobindin I
  • Placental anticoagulant protein I
  • Vascular anticoagulant-alpha
  • endonexin II
• GenBank acession
  • U05770
• Locus
  4q27
• Discovery year
  1989-05-31
• Entrez gene record
  308
• Pubmed identfication
  • 2960376
  • 14678296
• RefSeq identity
  • NM_001154
• Classification
  • Annexins
• VEGA ID
  OTTHUMG00000133034
• Locus Specific Databases
  • LRG_606

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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