Mouse anti NCAM / CD56
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Catalog numberMBS570110
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PricePlease ask
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[NCAM / CD56]
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ClonalityMonoclonal
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Clone[123C3]
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ReactivityHuman, Zebrafish
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Specificity123C3 was defined as a cluster I antibody during the First International Workshop on Small Cell Lung Cancer (SCLC) Antibodies. 123C3 recognizes an epitope in the NCAM exons 11-13 which is dependent on an intact conformation of the first fibronectin type-III homologous domain encoded by these exons. 123C3 stains NCAM which is present in small cell lung cancer and lung carcinoids. It also reacts with a number of non-small cell lung carcinomas and neuroendocrine and neuronal derived tissues. In addition, 123C3 is internalized after binding to its antigen on SCLC cell lines, making it an excellent reagent for tumor imaging in xenograft models.
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FormEach vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
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Storage_stabilityStore at 4 degree C, or in small aliquots at -20 degree C.
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Tested_applicationImmunocytochemistry (IHC), Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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Gene target
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Gene symbolNCAM1, L1CAM
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Short nameMouse anti NCAM / CD56
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TechniqueMouse, anti, antibody to, mouses
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HostMouse
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IsotypeIgG1
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SpeciesMouse, Mouses
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Alternative nameMouse antibody to NCAM / CD56
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Alternative techniquemurine, antibodies
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Gene info
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Identity
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Gene
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Long gene nameneural cell adhesion molecule 1
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Fibronectin type III domain containing
- CD molecules
- Ig-like cell adhesion molecule family
- I-set domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameL1 cell adhesion molecule
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Synonyms gene
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Synonyms gene name
- antigen identified by monoclonal antibody R1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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RefSeq identity
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Classification
- Ig-like cell adhesion molecule family
- I-set domain containing
- Fibronectin type III domain containing
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data