Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(N-8His)

• Catalog number
  CB20-1000
• Price
  Please ask
• Size
  1 mg

• Description
  Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein is produced by our Mammalian expression system and the target gene encoding Arg100-Leu233 is expressed with a 8His tag at the N-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  HHHHHHHHRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL
• Estimated molecular weight
  16,5 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  See included datasheet or contact us for more information.
• UniProt number
  P26715
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional description
  Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. 
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  NKG2-A/NKG2-B   Integral   Membrane   Protein   N-8His  
• Gene symbol
  KLRC1, KLRC4, KLRC3, KLRC2, KLRK1, PURG, SP140, EXOG, CCRL2, DGCR5
• Short name
  Recombinant NKG2-A/NKG2-B II Integral Protein(N-8His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Recombinant Human NKG2A/CD159A(N-8His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6374
• Gene
  KLRC1
• Long gene name
  killer cell lectin like receptor C1
• Synonyms gene
  • NKG2
• Synonyms gene name
  • killer cell lectin-like receptor subfamily C, member 1
• Synonyms
  • NKG2-A
  • NKG2-B
  • CD159a
• Synonyms name
  • NKG2-1/B activating NK receptor
• GenBank acession
  • U54782
• Locus
  12p13
• Discovery year
  1998-01-16
• Entrez gene record
  3821
• Pubmed identfication
  • 9598306
• RefSeq identity
  • NM_002259
• Classification
  • C-type lectin domain containing
  • CD molecules
  • Killer cell lectin like receptors
• VEGA ID
  OTTHUMG00000168584

Gene info

• Identity
  HGNC:6377
• Gene
  KLRC4
• Long gene name
  killer cell lectin like receptor C4
• Synonyms gene name
  • killer cell lectin-like receptor subfamily C, member 4
• Synonyms
  • NKG2-F
• GenBank acession
  • U96846
• Locus
  12p13.2
• Discovery year
  1998-09-03
• Entrez gene record
  8302
• Pubmed identfication
  • 9598306
• RefSeq identity
  • NM_013431
• Classification
  • Killer cell lectin like receptors
• VEGA ID
  OTTHUMG00000168575

Gene info

• Identity
  HGNC:6376
• Gene
  KLRC3
• Long gene name
  killer cell lectin like receptor C3
• Synonyms gene name
  • killer cell lectin-like receptor subfamily C, member 3
• Synonyms
  • NKG2-E
• GenBank acession
  • L14542
• Locus
  12p13.2
• Discovery year
  1998-01-16
• Entrez gene record
  3823
• Pubmed identfication
  • 9598306
• RefSeq identity
  • NM_002261
• Classification
  • C-type lectin domain containing
  • Killer cell lectin like receptors
• VEGA ID
  OTTHUMG00000167149

Gene info

• Identity
  HGNC:6375
• Gene
  KLRC2
• Long gene name
  killer cell lectin like receptor C2
• Synonyms gene name
  • killer cell lectin-like receptor subfamily C, member 2
• Synonyms
  • NKG2-C
  • CD159c
  • NKG2C
• Synonyms name
  • NKG2-C type II integral membrane protein
  • natural killer cell receptor G2-C
• GenBank acession
  • X54869
• Locus
  12p13.2
• Discovery year
  1998-01-16
• Entrez gene record
  3822
• Pubmed identfication
  • 9598306
• RefSeq identity
  • NM_002260
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168532

Gene info

• Identity
  HGNC:18788
• Gene
  KLRK1
• Long gene name
  killer cell lectin like receptor K1
• Synonyms gene
  • D12S2489E
• Synonyms gene name
  • DNA segment on chromosome 12 (unique) 2489 expressed sequence
  • killer cell lectin-like receptor subfamily K, member 1
• Synonyms
  • NKG2D
  • KLR
  • NKG2-D
  • CD314
• GenBank acession
  • AJ001687
• Locus
  12p13.2
• Discovery year
  2003-12-12
• Entrez gene record
  22914
• Pubmed identfication
  • 9683661
  • 2007850
• RefSeq identity
  • NM_007360
• Classification
  • Killer cell lectin like receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000168574

Gene info

• Identity
  HGNC:17930
• Gene
  PURG
• Long gene name
  purine rich element binding protein G
• Synonyms
  • PURG-A
  • PURG-B
• GenBank acession
  • AF195513
• Locus
  8p12
• Discovery year
  2004-02-09
• Entrez gene record
  29942
• Pubmed identfication
  • 12034829
• RefSeq identity
  • NM_013357
• VEGA ID
  OTTHUMG00000157357

Gene info

• Identity
  HGNC:17133
• Gene
  SP140
• Long gene name
  SP140 nuclear body protein
• Synonyms
  • LYSP100-B
  • LYSP100-A
• GenBank acession
  • U63420
• Locus
  2q37.1
• Discovery year
  2001-11-07
• Entrez gene record
  11262
• Pubmed identfication
  • 8695863
  • 8910577
  • 12368356
• RefSeq identity
  • NM_007237
• Classification
  • Bromodomain containing
  • PHD finger proteins
• VEGA ID
  OTTHUMG00000153670

Gene info

• Identity
  HGNC:3347
• Gene
  EXOG
• Long gene name
  exo/endonuclease G
• Synonyms gene
  • ENDOGL1
  • ENDOGL2
• Synonyms gene name
  • endonuclease G-like 1
  • endonuclease G-like 2
  • endo/exonuclease (5'-3'), endonuclease G-like
• Synonyms
  • ENGL-a
  • ENGL
  • ENGL-b
• GenBank acession
  • AB020523
• Locus
  3p22.2
• Discovery year
  1999-05-25
• Entrez gene record
  9941
• Pubmed identfication
  • 10231028
  • 18187503
• RefSeq identity
  • NM_005107
• VEGA ID
  OTTHUMG00000131295

Gene info

• Identity
  HGNC:1612
• Gene
  CCRL2
• Long gene name
  C-C motif chemokine receptor like 2
• Synonyms gene name
  • chemokine (C-C motif) receptor-like 2
• Synonyms
  • HCR
  • CRAM-B
  • CKRX
  • CRAM-A
  • ACKR5
• Synonyms name
  • atypical chemokine receptor 5
• GenBank acession
  • AF014958
• Locus
  3p21.31
• Discovery year
  1999-09-17
• Entrez gene record
  9034
• Pubmed identfication
  • 9473515
• Classification
  • Atypical chemokine receptors
• VEGA ID
  OTTHUMG00000156318

Gene info

• Identity
  HGNC:16757
• Gene
  DGCR5
• Long gene name
  DiGeorge syndrome critical region gene 5
• Synonyms gene
  • DGCR9
  • DGCR10
• Synonyms gene name
  • DiGeorge syndrome critical region gene 5 (non-protein coding)
  • DiGeorge syndrome critical region gene 9
  • DiGeorge syndrome critical region gene 9 (non-protein coding)
  • DiGeorge syndrome critical region gene 10
  • DiGeorge syndrome critical region gene 10 (non-protein coding)
• Synonyms
  • NCRNA00037
  • LINC00037
  • X91348
  • DGS-A
  • POM121L5P
  • DGS-B
• Synonyms name
  • non-protein coding RNA 37
  • long intergenic non-protein coding RNA 37
• GenBank acession
  • X91348
• Locus
  22q11.21
• Discovery year
  2002-04-22
• Entrez gene record
  26220
• Pubmed identfication
  • 8659529
  • 27898409
  • 29030962
• RefSeq identity
  • NR_002733
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000149977

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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