AMACR/ p504S Antibody

• Catalog number
  GEN438274
• Price
  Please ask
• Size
  100ug

• Also known as
  AMACR
• Other names
  alpha-methylacyl-CoA racemase isoform 3; Alpha-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase; 2-methylacyl-CoA racemase
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  AMACR
• Gene name synonims
  N/A
• Other gene names
  AMACR; AMACR; RM; RACE; CBAS4; AMACRD; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  13H4
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  Western Blot (WB), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AMACR   p504S  
• Gene symbol
  C1QTNF3-AMACR, AMACR
• Short name
  AMACR/ p504S Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-AMACR/ p504S
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:49198
• Gene
  C1QTNF3-AMACR
• Long gene name
  C1QTNF3-AMACR readthrough (NMD candidate)
• Locus
  5p13.2
• Discovery year
  2013-09-30
• Entrez gene record
  100534612
• VEGA ID
  OTTHUMG00000186337

Gene info

• Identity
  HGNC:451
• Gene
  AMACR
• Long gene name
  alpha-methylacyl-CoA racemase
• Synonyms
  • RACE
  • P504S
• GenBank acession
  • AF047020
• Locus
  5p13.2
• Discovery year
  1999-10-19
• Entrez gene record
  23600
• Pubmed identfication
  • 9307041
• RefSeq identity
  • NM_014324
• VEGA ID
  OTTHUMG00000090734

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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