Recombinant Human EGF Receptor (EGFR)

Available sizes

2ug:66,10ug:171
Store

store in freezer for long therm or fridge for short time storage
Category

research antibodies, ELISAs, e. Coli rec. human proteins
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

EGF Receptor EGFR
Gene symbol

EGF, EGFR-AS1, EGILA, EGFR, RHBDF1
Short name

Recombinant EGF Receptor (EGFR)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. genways bulk advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens epidermal growth factor Receptor (epidermal growth factor receptor)
Alternative technique

rec
Alternative to gene target

epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217

Identity

HGNC:3236
Gene

EGFR
Long gene name

epidermal growth factor receptor
Synonyms gene
- ERBB
Synonyms gene name
- epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
Synonyms
- ERBB1
- ERRP
Synonyms name
- erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)
- erb-b2 receptor tyrosine kinase 1
Locus

7p11.2
Discovery year

1986-01-01
Entrez gene record

1956
Pubmed identfication
- 1505215
RefSeq identity
- NM_005228
Classification
- Erb-b2 receptor tyrosine kinases
VEGA ID

OTTHUMG00000023661
Locus Specific Databases
- LRG_304

Identity

HGNC:20561
Gene

RHBDF1
Long gene name

rhomboid 5 homolog 1
Synonyms gene
- C16orf8
Synonyms gene name
- chromosome 16 open reading frame 8
- rhomboid family 1 (Drosophila)
- rhomboid 5 homolog 1 (Drosophila)
Synonyms
- EGFR-RS
- FLJ2235
- Dist1
- iRhom1
GenBank acession
- BC014425
Locus

16p13.3
Discovery year

2003-04-07
Entrez gene record

64285
Pubmed identfication
- 8318735
- 15965977
RefSeq identity
- NM_022450
Classification
- Rhomboid family
VEGA ID

OTTHUMG00000060719

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data