SIN1 Antibody
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Catalog numberN1067-100UG
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
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FormPurified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenSIN1
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat, Dog ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB
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Recommended dilutionsWestern blot: 1-3ug/ml
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NotesProvided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results.
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Added buffer1X Phosphate Buffered Saline (PBS), pH 7.4
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Intented useThis SIN1 antibodyis to be used only for research purposes and not for diagnostics..
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Gene ID79109
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PurityThis antibody was purified by Protein A method
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DescriptionmTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
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ImmunogenA recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
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StorageAliquot and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMAPKAP1
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Short nameAnti-SIN1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to SIN1
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameMAPK associated protein 1
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Synonyms gene name
- mitogen-activated protein kinase associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-07-19
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Entrez gene record
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Pubmed identfication
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Classification
- MTOR complex 2
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data