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FIIN 2 for cell activation

FIIN 2 for cell activation is available 2 times from Biovision labs

9577-25 | FIIN-2 for cell activation size: 25 mg | 717.07 USD

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9577-5 | FIIN-2 for cell activation size: 5 mg | 223.52 USD

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Other name N-(4-((3-(3,5-dimethoxyphenyl)-7-((4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide
Supplied with N/A
Description FIIN-2 is a potent, selective, irreversible, next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547.
Category Biochemicals
Molecular formula C₃₅H₃₈N₈O₄
Is it cell-permeable? Yes
Molecular weight 634.73
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 1633044-56-0
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Crystalline solid
Reconstitute instructions DMSO >6 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetFIIN-2 for activation
Short name FIIN-2 for activation
Technique activation
Alternative name FIIN-2 to measure cellular activation
Tissue cell
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