Human CellExp™ CD30 Ligand / TNFSF8, Human Recombinant

  • Catalog number
    P1462-10
  • Price
    Please ask
  • Size
    10 µg
  • Synonyms
    CD30-L, CD153, TNFSF8, CD30L, CD30LG, CD153 antigen, CD30 antigen ligand, CD30 Ligand
  • Alternative_names
    CD30-L, CD153, TNFSF8, CD30L, CD30LG, CD153 antigen, CD30 antigen ligand, CD30 Ligand
  • Description
    A ligand for TNFRSF8/CD30, which is a cell surface antigen
  • Recombinant
    True
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
    >90%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    Less than 1.0 EU per ug by the LAL method.
  • Molecular Weight
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.5 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Storage Temp
    -20ºC
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized powder
  • Physical form description
    Lyophilized
  • Reconstitution Instructions
    Reconstitute in sterile deionized water to the desired protein concentration.
  • Background Information
    CD30 ligand (CD30L) and CD30 are interacting cellsurface glycoproteins that are members of the tumour necrosis factor (TNF) and tumour necrosis factor receptor (TNFR) superfamilies. In humans, CD30L is expressed at high levels on activated T cells. There is conflicting evidence with regard to cell surface expression of CD30L on primary human B cells. An initial report of constitutive CD30L expression on peripheral blood B cells33 has not been substantiated.
  • Amino acid sequence
    Gln 63 - Asp 234
  • Handling
    Centrifuge the vial prior to opening.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Additional description
    FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    TNFSF8, TNFRSF8
  • Short name
    CellExp™ CD30 Ligand / TNFSF8, Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Humans
  • Alternative name
    H. sapiens CellExp™ CD30 Ligand / tumor necrosis factor (ligand) superfamily, member 8, H. sapiens Rec.
  • Alternative technique
    rec
  • Alternative to gene target
    tumor necrosis factor (ligand) superfamily, member 8, CD153 and CD30L and CD30LG, TNFSF8 and IDBG-82328 and ENSG00000106952 and 944, protein binding, Extracellular, Tnfsf8 and IDBG-155788 and ENSMUSG00000028362 and 21949, BT.44261 and IDBG-638653 and ENSBTAG00000025782 and 574056
Gene info
  • Identity
  • Gene
  • Long gene name
    TNF superfamily member 8
  • Synonyms gene
  • Synonyms gene name
    • tumor necrosis factor (ligand) superfamily, member 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1993-11-08
  • Entrez gene record
    944
  • Pubmed identfication
  • Classification
    • Tumor necrosis factor superfamily
    • CD molecules
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    TNF receptor superfamily member 8
  • Synonyms gene
  • Synonyms gene name
    • tumor necrosis factor receptor superfamily, member 8
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1992-01-10
  • Entrez gene record
    943
  • Pubmed identfication
  • Classification
    • CD molecules
    • Tumor necrosis factor receptor superfamily
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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