Protein L Magnetic Beads

• Catalog number
  6537-1
• Price
  Please ask
• Size
  1 ml

• Description
  Reusable Protein L conjugated magnetic beads with ≥10 mg/ml binding capacity for antibody purification from multiple sources. Protein L Magnetic Beads are prepared by covalently coupling Recombinant Protein L (contains five Ig kappa light chain binding domains, BV catalog # 6530) to 6% crosslinked magnetically beaded agarose. The coupling technique is optimized to give a high binding capacity. The capacity of IgG binding is generally greater than 10 mg of human IgG per ml of wet gel.
• Product Highlights
  • CONTENTS: Supplied as a 50% slurry in PBS with 0.02% sodium azide. • TECHNICAL SPECIFICATIONS: Support Characteristics- Paramagnetic, spherical, 6 % cross-linked agarose Ligand- Recombinant Protein L Particle Size- 75 – 150 µm Binding Capacity- Generally >10 mg human IgG/ml wet beads Working Temperature- Room temperature Storage Solution- PBS with 0.02% NaN₃ • FEATURES: Easy to use, high-binding capacity, non-adherent beads. Useful for immunoprecipitation and enrichment of antibodies. High affinity for kappa-light chain containing Ig antibodies from a variety of species. Protein L binds to all IgG subclasses from human, mouse and rat species. It also binds to human, mouse and rat IgM, IgA, IgE and IgD, as well as FAB with Kappa-light chains. Protein L is superior for binding chicken, hamster and pig IgG.
• Storage Temp
  +4°C
• Shipping
  gel pack
• Shelf Life
  12 months
• Datasheet
• Notes
  For research use only. Not to be used for human or animal treatment or consumption.
• Conjugation
  Magnetic beads

• Gene target
  Protein  
• Gene symbol
  LCP1, PGLYRP2, ATRN
• Short name
  Protein L
• Technique
  All kind of bead conjugates are available, magnetic, borosilicate, agarose protein A. magnetic beads can be isolated by a macs type magnet. Magnetic bead separation is a quick, efficient, clean process that scientists use to replace filtration, centrifugation and separation techniques. Magnetic beads and particles are used as carriers of antigens, antibodies, catalyzers, proteins and nucleic acids, enabling action on cells, bacteria, viruses and other biological entities.
• Label
  Magnetic
• Alternative name
  Protein L Magnetic particles

Gene info

• Identity
  HGNC:6528
• Gene
  LCP1
• Long gene name
  lymphocyte cytosolic protein 1
• Synonyms gene name
  • lymphocyte cytosolic protein 1 (L-plastin)
• Synonyms
  • PLS2
  • CP64
  • L-PLASTIN
  • LC64P
• Synonyms name
  • plastin 2
• GenBank acession
  • M22300
• Locus
  13q14.13
• Discovery year
  1986-01-01
• Entrez gene record
  3936
• Pubmed identfication
  • 2111166
• RefSeq identity
  • NM_002298
• Classification
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000016864

Gene info

• Identity
  HGNC:30013
• Gene
  PGLYRP2
• Long gene name
  peptidoglycan recognition protein 2
• Synonyms
  • PGRP-L
  • PGLYRPL
  • TAGL-like
  • tagL
  • tagL-alpha
  • tagl-beta
  • PGRPL
• Synonyms name
  • peptidoglycan recognition protein L precursor
  • peptidoglycan recognition protein-like
  • N-acetylmuramoyl-L-alanine amidase
• GenBank acession
  • AY358156
• Locus
  19p13.12
• Discovery year
  2004-03-17
• Entrez gene record
  114770
• Pubmed identfication
  • 11461926
  • 12669421
  • 14506276
• RefSeq identity
  • NM_052890
• Classification
  • Peptidoglycan recognition proteins
• VEGA ID
  OTTHUMG00000150690

Gene info

• Identity
  HGNC:885
• Gene
  ATRN
• Long gene name
  attractin
• Synonyms
  • DPPT-L
  • MGCA
• Synonyms name
  • mahogany protein
• GenBank acession
  • AF034957
• Locus
  20p13
• Discovery year
  1998-10-30
• Entrez gene record
  8455
• Pubmed identfication
  • 9736737
  • 8596018
• RefSeq identity
  • NM_139321
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000031746

MeSH Data

• Name
  Immunomagnetic Separation
• Concept
  Scope note: A cell-separation technique where magnetizable microspheres or beads are first coated with monoclonal antibody, allowed to search and bind to target cells, and are then selectively removed when passed through a magnetic field. Among other applications, the technique is commonly used to remove tumor cells from the marrow (BONE MARROW PURGING) of patients who are to undergo autologous bone marrow transplantation.
• Tree numbers
  • E02.095.437
  • E05.200.500.363.441
  • E05.242.363.441
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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