Boc-3-hydroxy-1-adamantyl-L-glycine

Chemical available in other sizes

Please inquire size and price
Stock availability

Please Inquire
Cas number

1334321-39-9
Chemical s molecular weight

325.4
Chemical s main applications

Boc-3-hydroxy-1-adamantyl-L-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
Other name

(2R)-2-((tert-Butoxycarbonyl)amino)-2-(3-hydroxyadamantan-1-yl)acetic Acid; (αR)-α-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxy-tricyclo[3.3.1.13,7]decane-1-acetic Acid
Chemical s formula

C17H27NO5
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

Boc-3-hydroxy-1-adamantyl-L-glycine
Gene symbol

L3MBTL2, CPT1A, POM121L2, RPL12P1, CLDN10, MLPH, RPL32P1, FABP1, H2BC4, COX7A2
Short name

Boc-3-hydroxy-1-adamantyl-L-glycine
Alternative name

Boc homolog (mouse)-3-hydroxy-1-adamantyl-L-glycine
Alternative to gene target

Boc homolog (mouse), BOC and IDBG-50192 and ENSG00000144857 and 91653, protein binding, Plasma membranes, Boc and IDBG-162156 and ENSMUSG00000022687 and 117606, BOC and IDBG-632359 and ENSBTAG00000013909 and 512018

Identity

HGNC:18594
Gene

L3MBTL2
Long gene name

L3MBTL histone methyl-lysine binding protein 2
Synonyms gene name
- l(3)mbt-like 2 (Drosophila)
- L3MBTL2, polycomb repressive complex 1 subunit
Synonyms
GenBank acession
- AJ305226
Locus

22q13.2
Discovery year

2002-04-29
Entrez gene record

83746
Pubmed identfication
- 11682070
- 21596310
RefSeq identity
- NM_031488
Classification
- MBT domain containing
VEGA ID

OTTHUMG00000150942

Identity

HGNC:13973
Gene

POM121L2
Long gene name

POM121 transmembrane nucleoporin like 2
Synonyms gene name
- POM121 membrane glycoprotein-like 2 (rat)
- POM121 membrane glycoprotein-like 2
- POM121 transmembrane nucleoporin-like 2
Synonyms
- POM121-L
GenBank acession
- AL021808
Locus

6p22.1
Discovery year

2001-07-20
Entrez gene record

94026
RefSeq identity
- NM_033482
VEGA ID

OTTHUMG00000014475

Identity

HGNC:29643
Gene

MLPH
Long gene name

melanophilin
Synonyms
- l1Rk3
- l(1)-3Rk
- Slac-2a
- ln
- exophilin-3
GenBank acession
- AY358857
Locus

2q37.3
Discovery year

2004-01-09
Entrez gene record

79083
Pubmed identfication
- 11980908
- 11504925
RefSeq identity
- NM_024101
Classification
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000133298
Locus Specific Databases
- MLPHbase: Mutation registry for Griscelli syndrome, type 3 (GS3)
- LRG_83

Identity

HGNC:4757
Gene

H2BC4
Long gene name

H2B clustered histone 4
Synonyms gene
- H2BFL
- HIST1H2BC
Synonyms gene name
- H2B histone family, member L
- histone 1, H2bc
- histone cluster 1, H2bc
- histone cluster 1 H2B family member c
Synonyms
- H2B/l
- H2B.1
GenBank acession
- Z80783
Locus

6p22.2
Discovery year

1998-09-07
Entrez gene record

8347
Pubmed identfication
- 9119399
- 12408966
RefSeq identity
- NM_003526
Classification
- H2B histones
VEGA ID

OTTHUMG00000014425