Rabbit Anti-Human CDK7 (pThr170) Polyclonal: PE/ATTO 594

  • Catalog number
    SPC-945D-P594
  • Price
    Please ask
  • Size
    100 µl
  • Immunogen
    A phospho-specific peptide corresponding to residues surrounding Thr170 of human CDK7 (AA167-173)
  • Antibody s target
    Human CDK7 (pThr170)
  • Antibody s full description
    Rabbit Anti-Human CDK7 (pThr170) Polyclonal
  • Antibody s category
    Polyclonal Antibodies
  • Antibody s other name
    39 kDa protein kinase Antibody, CAK Antibody, CAK1 Antibody, Cdk activating kinase Antibody, CDK7_HUMAN Antibody, Cell division protein kinase 7 Antibody, Cyclin dependent kinase 7 Antibody, HCAK Antibody, MO15 Antibody, P39 Mo15 Antibody, Serine threonine kinase Stk1 Antibody, STK1 Antibody, TFIIH basal transcription factor complex kinase subunit Antibody
  • Verified applications
    WB, AM
  • Raised in
    Rabbit
  • Antibody s reactivity
    Human
  • Antibody s recommended dilutions for use
    WB (1:250); optimal dilutions for assays should be determined by the user.
  • Antibody s purified from
    Peptide Affinity Purified
  • Recommended buffer for storage
    PBS pH7.4, 50% glycerol, 0.025% Thimerosal
  • Antibody s concentration
    See included datasheet or contact our support service
  • Antibody s specificity
    Detects ~39kDa.
  • Storage recommendations
    -20°C
  • Shipping recommendations
    Blue Ice or 4°C
  • Certificate of analysis
    A 1:250 dilution of SPC-945 was sufficient for detection of CDK7 (pThr170) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
  • Antibody in cell
    Nucleus
  • Tissue specificity
    Ubiquitous
  • Scientific context
    CDK7 is a protein-serine/threonine kinase. CDK7 has been identified as the mammalian homolog of MO15, a protein kinase demonstrated in starfish and Xenopus. The regulatory subunit is a novel cyclin (cyclin H) and is required for activation of CDK7. Like other Cdks, CDK7 contains a conserved threonine residue required for full activity; mutation of this residue severely reduces CAK activity.
  • Bibliography
    Refer to PubMed
  • Released date
    29/Aug/2016
  • NCBI number
    NP_001790
  • Gene number
    1022
  • Protein number
    P50613
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Antibody s datasheet
    Contact our support service to receive datasheet or other technical documentation.
  • Representative figure link
    No Data Available
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    1.4
  • Net weight g
    0.1
  • Stock availabilit
    In Stock
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Test
    StressMark antibodies supplies antibodies that are for research of human proteins.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
  • Latin name
    Oryctolagus cuniculus
  • Gene target
    CDK7   pThr170   PE/ATTO   594  
  • Gene symbol
    CDK7
  • Short name
    Rabbit Anti- CDK7 (pThr170) Polyclonal: PE/ATTO 594
  • Technique
    anti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Host
    Rabbit, Rabbits
  • Isotype
    Immunoglobulin
  • Label
    PE/ATTO 594
  • Species
    Human, Humans
  • Alternative name
    production species: rabbit Antibody toHuman CDK7 (pThr170) polyclonal: peroxidase/ATTO 594
  • Alternative technique
    polyclonals, rabbit-anti, antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    cyclin dependent kinase 7
  • Synonyms gene name
    • cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
    • cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
  • Synonyms
  • Locus
  • Discovery year
    1994-12-16
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Cyclin dependent kinases
    • CDK activating kinase complex
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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