Rabbit Anti-Human CDK7 (pThr170) Polyclonal: PE/ATTO 594
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Catalog numberSPC-945D-P594
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PricePlease ask
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Size100 µl
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ImmunogenA phospho-specific peptide corresponding to residues surrounding Thr170 of human CDK7 (AA167-173)
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Antibody s targetHuman CDK7 (pThr170)
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Antibody s full descriptionRabbit Anti-Human CDK7 (pThr170) Polyclonal
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Antibody s categoryPolyclonal Antibodies
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Antibody s other name39 kDa protein kinase Antibody, CAK Antibody, CAK1 Antibody, Cdk activating kinase Antibody, CDK7_HUMAN Antibody, Cell division protein kinase 7 Antibody, Cyclin dependent kinase 7 Antibody, HCAK Antibody, MO15 Antibody, P39 Mo15 Antibody, Serine threonine kinase Stk1 Antibody, STK1 Antibody, TFIIH basal transcription factor complex kinase subunit Antibody
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Verified applicationsWB, AM
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Raised inRabbit
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Antibody s reactivityHuman
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Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
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Antibody s purified fromPeptide Affinity Purified
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Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
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Antibody s concentrationSee included datasheet or contact our support service
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Antibody s specificityDetects ~39kDa.
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Storage recommendations-20°C
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Shipping recommendationsBlue Ice or 4°C
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Certificate of analysisA 1:250 dilution of SPC-945 was sufficient for detection of CDK7 (pThr170) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Antibody in cellNucleus
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Tissue specificityUbiquitous
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Scientific contextCDK7 is a protein-serine/threonine kinase. CDK7 has been identified as the mammalian homolog of MO15, a protein kinase demonstrated in starfish and Xenopus. The regulatory subunit is a novel cyclin (cyclin H) and is required for activation of CDK7. Like other Cdks, CDK7 contains a conserved threonine residue required for full activity; mutation of this residue severely reduces CAK activity.
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BibliographyRefer to PubMed
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Released date29/Aug/2016
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NCBI numberNP_001790
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Gene number1022
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Protein numberP50613
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
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Representative figure linkNo Data Available
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg1.4
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Net weight g0.1
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Stock availabilitIn Stock
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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TestStressMark antibodies supplies antibodies that are for research of human proteins.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolCDK7
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Short nameRabbit Anti- CDK7 (pThr170) Polyclonal: PE/ATTO 594
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Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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IsotypeImmunoglobulin
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LabelPE/ATTO 594
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SpeciesHuman, Humans
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Alternative nameproduction species: rabbit Antibody toHuman CDK7 (pThr170) polyclonal: peroxidase/ATTO 594
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Alternative techniquepolyclonals, rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene namecyclin dependent kinase 7
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Synonyms gene name
- cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
- cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
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Synonyms
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Locus
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Discovery year1994-12-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cyclin dependent kinases
- CDK activating kinase complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data