GAAP Antibody

• Catalog number
  3524-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  GAAP
• Target Alternative Name
  Golgi anti-apoptotic protein, Protein S1R, Transmembrane BAX inhibitor motif-containing protein 4, Z-protein
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide at N-terminal
• Accession
  P55061
• Gene Id
  7009
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Western blot: Jurkat cell lysate, 3T3 cell lysate
• Application And Usages
  Western blot: 1:200
• Description
  The BI-1 (Bax inhibitor 1) family is evolutionarily conserved as integral membrane proteins containing multiple membrane-spanning domains that are predominantly localized to intracellular membranes. BI-1 family members share multiple motifs and transcriptional factors within the promoter and the coding regions. They represent regulators of cell death pathways and are highly conserved in evolution from plants to insects, amphibians, mammals and pox-viruses. GAAP (Golgi anti-apoptotic protein), also known as TMBIM4 (transmembrane Bax inhibitor motif containing 4), S1R, ZPRO or CGI-119, is a 238 amino acid multi-pass membrane protein that belongs to the BI-1 family. Ubiquitously expressed, GAAP inhibits apoptosis induced by intrinsic and extrinsic apoptotic stimuli.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GAAP  
• Gene symbol
  TMBIM4
• Short name
  GAAP Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  GAAP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24257
• Gene
  TMBIM4
• Long gene name
  transmembrane BAX inhibitor motif containing 4
• Synonyms
  • CGI-119
  • S1R
  • ZPRO
  • LFG4
  • GAAP
• GenBank acession
  • AF113127
• Locus
  12q14.3
• Discovery year
  2005-08-22
• Entrez gene record
  51643
• Pubmed identfication
  • 11042152
  • 10810093
• RefSeq identity
  • NM_016056
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000168973

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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