Human CellExp™ ROR1 (39-151, Ig-like domain), Human Recombinant
-
Catalog numberP1251-10
-
PricePlease ask
-
Size10 ug
-
-
SynonymsROR1, NTRKR1
-
Alternative_namesROR1, NTRKR1
-
DescriptionReceptor for wnt ligand WNT5A
-
RecombinantYes
-
SourceHEK293 cells
-
Purity by SDS PAGE≥95%
-
AssaySDS-PAGE
-
Molecular Weight13.4 kDa
-
Storage Temp-20°C
-
ShippingGel Pack
-
Shelf Life12 months
-
AppearanceLyophilized
-
Physical form descriptionLyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
-
Reconstitution InstructionsCentrifuge the vial prior to opening. Reconstitute in distilled water.
-
Background InformationTyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
-
HandlingCentrifuge the vial prior to opening.
-
UsageFor Research Use Only! Not to be used in humans
-
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Additional sourceRecombinants or rec. proteins
-
Grouprecombinants
-
Gene target
-
Gene symbolSNORD115-39, ROR1, ROR1-AS1, IGKV1-39, IGKV1D-39, IGHV4-39, ZNF140, VIPAS39, PALLD, CHI3L2
-
Short nameCellExp™ ROR1 (39-151, Ig-like domain), Recombinant
-
TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
SpeciesHumans
-
Alternative nameH. sapiens CellExp™ ROR1 (39-151, Ig-like domain), H. sapiens Rec.
-
Alternative techniquerec
-
Gene info
-
Identity
-
Gene
-
Long gene namesmall nucleolar RNA, C/D box 115-39
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2007-02-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Small nucleolar RNAs, C/D box
Gene info
-
Identity
-
Gene
-
Long gene namereceptor tyrosine kinase like orphan receptor 1
-
Synonyms gene
-
GenBank acession
-
Locus
-
Discovery year2000-02-29
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- I-set domain containing
- Receptor tyrosine kinases
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameROR1 antisense RNA 1
-
Locus
-
Discovery year2014-05-21
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Antisense RNAs
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 1-39
-
Synonyms gene name
- immunoglobulin kappa variable 1-39 (gene/pseudogene)
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin kappa locus at 2p11.2
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 1D-39
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin kappa locus at 2p11.2
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable 4-39
-
GenBank acession
-
Locus
-
Discovery year2000-04-04
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namezinc finger protein 140
-
Synonyms gene name
- zinc finger protein 140 (clone pHZ-39)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1993-02-11
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Zinc fingers C2H2-type
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameVPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
-
Synonyms gene
-
Synonyms gene name
- chromosome 14 open reading frame 133
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year2003-01-28
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namepalladin, cytoskeletal associated protein
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2005-11-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- I-set domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namechitinase 3 like 2
-
Synonyms gene name
- chitinase 3-like 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-12-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Chitinases
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
