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PJ 34 PARP inhibitor

PJ 34 PARP inhibitor is available 2 times from Stressma labs

SIH-366-10MG | PJ-34, PARP inhibitor size: 10 mg | 273.21 USD

Catalog number SIH-366-10MG
Supplier stressma
Price 273.21 USD
Size 10 mg
Net weight (g) 0.01
1. Gene info
Identity33053
Synonyms
GenBank acession
Locus15q11.2
Discovery year2007-02-15
Pubmed identfication
RefSeq identity
2. Gene info
Identity270
GenePARP1
Synonyms gene
Synonyms gene name
  • ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
  • poly (ADP-ribose) polymerase family, member 1
Synonyms
GenBank acession
Locus1q42.12
Discovery year1986-01-01
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000037556

SIH-366-50MG | PJ-34, PARP inhibitor size: 50 mg | 881.56 USD

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Origin Synthetic
Soluble in May be dissolved in DMSO (30 mg/ml) or water (20 mg/ml)
Other name N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,Ndimethylacetamide . HCl
PubMed number Refer to PubMed
Description PARP inhibitor
Warning information Non-hazardous
Representative figure legend Chemical structure of PJ-34 (SIH-366), a PARP inhibitor. CAS #: 344458-15-7. Molecular Formula: C17H17N3O2 *HCL * H2O. Molecular Weight: 331.8 g/mol. Chemical structure of PJ-34, a PARP inhibitor (SIH-366). CAS # 344458-15-7. Molecular Formula: C17H17N3O2 *HCL * H2O.
Stock availabilitIn Stock In Stock
Molecular weight 331,8 g/mol
Purity pourcentage ≥98% (HPLC); NMR (Conforms)
Chemical formula C17H17N3O2•HCL•H2O
Tested applications To be tested
Primary research fields Cancer, Apoptosis, Cancer Growth Inhibitors, PARP Inhibitors
Total weight (kg) 0.25
Release date 4-Apr-2013
Scientific context PJ-34 is a selective inhibitor of Poly (ADP-Ribose) polymerase (PARP). Studies have shown that the use of PJ-34 on severe inflammatory diseases, in particular experimental allergic encephalomyelitis (EAE) have contributed to a shift of the immune response from a pro-inflammatory Th1 to anti-inflammatory th2 phenotype (1).
Product type Inhibitor
CAS number 344458-15-7
Safety information Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Country of production Canada
Product category Small Molecules
Physical appearance White to yellow solid.
Tested reactivity To be tested
PubChem number 4858
Bibliography 1. Scott G., Kean R., Mikheeva., Fabis M., Mabley J.J. (2004) The Journal of Pharmacology and Exp. Therapeutics. 310(3): 1053-1061.
Storage recommendations -20ºC
Shipping recommendations Shipped Ambient
Additional description Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
Gene targetPJ-34 PARP inhibitor
Short name PJ-34, PARP inhibitor
Alternative name PJ-34, PARP suppressor
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PJ-34, PARP inhibitor size: 10 mg - Gentaur.com
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