PINK1 Antibody

• Catalog number
  F49623-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  PINK1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC, WB, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This PINK1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q9BXM7
• Purity
  Purified
• Description
  Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
• Immunogen
  A portion of amino acids 118-147 from the human protein was used as the immunogen for this PINK1 antibody.
• Storage
  Store at 4oC for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PINK1  
• Gene symbol
  PINK1-AS, PINK1
• Short name
  Anti-PINK1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to PINK1
• Alternative technique
  antibodies
• Alternative to gene target
  PTEN induced putative kinase 1, PINK1 and IDBG-92922 and ENSG00000158828 and 65018, transferase activity, nuclei, Pink1 and IDBG-199773 and ENSMUSG00000028756 and 68943, PINK1 and IDBG-645657 and ENSBTAG00000006084 and 510683

Gene info

• Identity
  HGNC:38872
• Gene
  PINK1-AS
• Long gene name
  PINK1 antisense RNA
• Synonyms gene
  • PINK1-AS1
• Synonyms gene name
  • PINK1 antisense RNA 1 (non-protein coding)
  • PINK1 antisense RNA (non-protein coding)
• Synonyms
  • FLJ00387
  • PINK1AS
  • naPINK1
• GenBank acession
  • AK090466
• Locus
  1p36.12
• Discovery year
  2010-08-19
• Pubmed identfication
  • 17362513
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000002840

Gene info

• Identity
  HGNC:14581
• Gene
  PINK1
• Long gene name
  PTEN induced kinase 1
• Synonyms gene
  • PARK6
• Synonyms gene name
  • Parkinson disease (autosomal recessive) 6
  • PTEN induced putative kinase 1
• Synonyms
  • BRPK
• GenBank acession
  • AB053323
• Locus
  1p36.12
• Discovery year
  2001-02-08
• Entrez gene record
  65018
• Pubmed identfication
  • 24751536
  • 11494141
  • 15349860
  • 14607334
• RefSeq identity
  • NM_032409
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000002841
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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