C19orf46 Antibody, ALEXA FLUOR 350

• Catalog number
  bs-9682R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  C19orf46 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-C19orf46 PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  C19orf46
• Specificity
  This is a highly specific antibody against C19orf46.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C19orf46
• Gene ID Number
  163183
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localization of the nucleus. C19orf46 interacts with UKHC and KCL1, and exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear enevelop targeting and binds to the SUN domain of SUN1 and SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  Nesprin-4; Nesprin4; Nesprin 4; Chromosome 19 open reading frame 46; FLJ36445; Hypothetical protein LOC163183; SYNE4_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• French translation
  anticorps

• Gene target
  C19orf46  
• Gene symbol
  SYNE4
• Short name
  Anti-C19orf46
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  C19orf46 Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:26703
• Gene
  SYNE4
• Long gene name
  spectrin repeat containing nuclear envelope family member 4
• Synonyms gene
  • C19orf46
  • DFNB76
• Synonyms gene name
  • chromosome 19 open reading frame 46
  • deafness, autosomal recessive 76
• Synonyms
  • FLJ36445
  • Nesprin-4
  • Nesp4
• GenBank acession
  • BC038360
• Locus
  19q13.12
• Discovery year
  2006-07-12
• Entrez gene record
  163183
• Pubmed identfication
  • 23348741
• RefSeq identity
  • NM_001039876
• Classification
  • KASH domain containing
  • Spectrin repeat containing nuclear envelope family
• VEGA ID
  OTTHUMG00000048135
• Locus Specific Databases
  • LRG_1385

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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