Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr1217
This is a highly specific antibody against PLCG2Tyr1217.
PLCG2phospho Y1217; PLC Î³2Tyr1217; PLC gamma 2/PLCG2Tyr1217; PLC 2; PLC gamma 2; PLC IV; PLCG2; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2; EC 188.8.131.52; Phosphoinositide phospholipase C; Phospholipase C gamma 2; Phospholipase C, gamma 2 phosphatidylinositol specic; PLCG2_HUMAN.
Purified by Protein A.
Human, Mouse, Rat
Gene ID Number
Background of the antigen
Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.
1ug per 1ul
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Alternative to gene target
phospholipase C, gamma 2 (phosphatidylinositol-specific), APLAID and FCAS3 and PLC-gamma-2 and PLC-IV, PLCG2 and IDBG-43723 and ENSG00000197943 and 5336, phosphoric diester hydrolase activity, Plasma membranes, Plcg2 and IDBG-195070 and ENSMUSG00000034330 and 234779, PLCG2 and IDBG-629513 and ENSBTAG00000002103 and 100337091