PLCG2(Tyr1217) Antibody, ALEXA FLUOR 488

• Catalog number
  bs-3338R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  PLCG2(Tyr1217) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-PLCG2Tyr1217 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PLCG2Tyr1217
• Specificity
  This is a highly specific antibody against PLCG2Tyr1217.
• Modification
  Phosphorylation
• Modification Site
  Tyr1217
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr1217
• Gene ID Number
  5336
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  PLCG2phospho Y1217; PLC γ2Tyr1217; PLC gamma 2/PLCG2Tyr1217; PLC 2; PLC gamma 2; PLC IV; PLCG2; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2; EC 3.1.4.11; Phosphoinositide phospholipase C; Phospholipase C gamma 2; Phospholipase C, gamma 2 phosphatidylinositol specic; PLCG2_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-PLCG2Tyr1217 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  PLCG2   Tyr1217  
• Gene symbol
  PLCG2
• Short name
  Anti-PLCG2Tyr1217
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  PLCG2(Tyr1217) Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  phospholipase C, gamma 2 (phosphatidylinositol-specific), APLAID and FCAS3 and PLC-gamma-2 and PLC-IV, PLCG2 and IDBG-43723 and ENSG00000197943 and 5336, phosphoric diester hydrolase activity, Plasma membranes, Plcg2 and IDBG-195070 and ENSMUSG00000034330 and 234779, PLCG2 and IDBG-629513 and ENSBTAG00000002103 and 100337091

Gene info

• Identity
  HGNC:9066
• Gene
  PLCG2
• Long gene name
  phospholipase C gamma 2
• Synonyms gene name
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
• Locus
  16q24.1
• Discovery year
  1994-05-16
• Entrez gene record
  5336
• Pubmed identfication
  • 7835906
• Classification
  • C2 domain containing phospholipases
  • Phospholipases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000176532
• Locus Specific Databases
  • LRG_376

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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