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AT 101 for cell activation

AT 101 for cell activation is available 2 times from Biovision labs

2380-25 | AT-101 for cell activation size: 25 mg | 575.24 USD

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2380-5 | AT-101 for cell activation size: 5 mg | 186.07 USD

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Other name (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dim­ethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8­,8'-dicarboxaldehyde; (R)-Gossypol
Supplied with N/A
Description AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the antiapoptotic Bcl proteins (Bcl-2, Bcl-XL, Bcl-W, and Mcl-1) and an inducer of the pro-apoptotic proteins noxa and puma. It induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway.
Category Biochemicals
Molecular formula C₃₀H₃₀O₈
Is it cell-permeable? Yes
Molecular weight 518.56
Storage condition -20 ̊C
Shipping condition gel pack
Purification ≥98% by TLC
Peptide sequence N/A
Is this a salt? No
CAS number 90141-22-3
Storage instructions Protect from light and air
Maximum time for storage 36 months
Physical appearance Light brown solid
Reconstitute instructions DMSO (~50 mg/ml) or EtOH (~50 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetAT-101 for activation
Short name AT-101 for activation
Technique activation
Alternative name AT-101 to measure cellular activation
Tissue cell
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