GOAT ANTI HUMAN CLUSTERIN (C-TERMINAL)

• Catalog number
  MBS223574
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [CLUSTERIN]
• Other_names
  [clusterin preproprotein; Clusterin; clusterin; aging-associated protein 4; apolipoprotein J; complement cytolysis inhibitor; complement lysis inhibitor; complement-associated protein SP-40,40; ku70-binding protein 1; sulfated glycoprotein 2; testosterone-repressed prostate message 2; clusterin; Aging-associated gene 4 protein; Apolipoprotein J; Apo-J; Complement cytolysis inhibitor; CLI; Complement-associated protein SP-40,40; Ku70-binding protein 1; NA1/NA2; Testosterone-repressed prostate message 2; TRPM-2]
• Other_gene_names
  [CLU; CLU; CLI; AAG4; APOJ; CLU1; CLU2; KUB1; SGP2; APO-J; SGP-2; SP-40; TRPM2; TRPM-2; NA1/NA2; APOJ; CLI; KUB1; Apo-J; CLI; TRPM-2]
• Clonality
  Polyclonal
• Reactivity
  Dog (Expected from Sequence)
• Specificity
  This item specifically recognises an epitope within the C-terminal (CT) region of human clusterin, otherwise known as Apolipoprotein J, a ubiquitously expressed glycoprotein and member of the clusterin family, implicated in apoptosis (programmed cell death), cell-cell adhesion, DNA repair, membrane recycling, spermatogenesis, and the inhibition of complement-mediated cell lysis. Clusterin is a component of the SC5b-9 complex which plays a role in inhibiting the complement cascade, through the prevention of the binding of a C5b-C7 complex to the membrane of the target cell. Clusterin exists as both a pro-apoptotic form localised to the nucleus, and a pro-survival secreted form, and has been detected at elevated levels in Alzheimer's disease, atherosclerosis, myocardial infarction, and various cancers, including bladder, prostate, and breast tumours.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA), Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Latin name
  Capra aegagrus hircus
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  CLUSTERIN  
• Gene symbol
  CLUL1, CLU, CLUAP1
• Short name
  GOAT ANTI CLUSTERIN (C-TERMINAL)
• Technique
  anti human, anti, Goat, antibody to, anti human antibodies, goats
• Host
  Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
• Isotype
  IgG
• Species
  Human, Goats, Humans
• Alternative name
  caprine antibody to H. sapiens CLUSTERIN (C-TERMINAL)
• Alternative technique
  antibodies, caprine

Gene info

• Identity
  HGNC:2096
• Gene
  CLUL1
• Long gene name
  clusterin like 1
• Synonyms gene name
  • clusterin-like 1 (retinal)
• Synonyms name
  • retinal clusterin-like protein
• GenBank acession
  • D63813
• Locus
  18p11.32
• Discovery year
  2000-05-30
• Entrez gene record
  27098
• Pubmed identfication
  • 10675623
  • 14507903
• VEGA ID
  OTTHUMG00000178252

Gene info

• Identity
  HGNC:2095
• Gene
  CLU
• Long gene name
  clusterin
• Synonyms gene
  • CLI
  • APOJ
• Synonyms gene name
  • clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)
• Synonyms
  • SGP-2
  • SP-40
  • TRPM-2
  • KUB1
  • CLU1
  • CLU2
• Synonyms name
  • complement lysis inhibitor
  • sulfated glycoprotein 2
  • testosterone-repressed prostate message 2
  • apolipoprotein J
• GenBank acession
  • M64722
• Locus
  8p21.1
• Discovery year
  1990-07-26
• Entrez gene record
  1191
• Pubmed identfication
  • 1585460
• RefSeq identity
  • NM_001831
• Classification
  • Complement system regulators and receptors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000102114

Gene info

• Identity
  HGNC:19009
• Gene
  CLUAP1
• Long gene name
  clusterin associated protein 1
• Synonyms
  • FLJ13297
  • KIAA0643
  • FAP22
  • CFAP22
  • IFT38
• Synonyms name
  • flagellar associated protein 22, qilin-like protein, homolog (Chlamydomonas)
  • cilia and flagella associated protein 22
• GenBank acession
  • BC017070
• Locus
  16p13.3
• Discovery year
  2004-09-16
• Entrez gene record
  23059
• Pubmed identfication
  • 15480429
  • 19253336
• RefSeq identity
  • NM_024793
• Classification
  • IFT-B2 complex
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000177581

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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