APRIL, Recombinant, Mouse (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13)
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Catalog numberMBS650656
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PricePlease ask
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Size5x0.02 mg
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Products_typeActive Protein
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Products_short_name[APRIL]
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Other_names[acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; acidic leucine-rich nuclear phosphoprotein 32 family member B; silver-stainable protein SSP29; acidic protein rich in leucines; putative HLA-DR-associated protein I-2; acidic (leucine-rich) nuclear phosphoprotein 32 family, member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29]
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Other_gene_names[ANP32B; ANP32B; APRIL; SSP29; PHAPI2; APRIL; PHAPI2; PHAPI2]
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PurityHighly Purified98% by SDS-PAGE and HPLC analyses Endotoxin: 0.1ng/ug (1EU/ug)
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FormSupplied as a lyophilized powder from 10mM sodium phosphate, pH 5, 100mM arginine. Reconstitute in sterile dH2O to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers with carrier protein. Do not vortex..
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Storage_stabilityLyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with ddH2O, 0.1% BSA or HSA. Aliquot and store at -20 degree C. Reconstituted product is stable for 3 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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DescriptionFAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNF, TNFRSF1A, TNFRSF1B, TNFSF13, LTBR, ANP32B, TNFSF12-TNFSF13, TNFSF13B, MIR1289-2, MIR521-2
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Short nameAPRIL, Recombinant, Mouse (a Proliferation Ligand, TALL-2, TNF ApoL- Leukocyte-expressed Ligand 2, TRDL-1a, TNF- Death Ligand 1a, TNFSF13)
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TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Hostmouse
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SpeciesMouse, Mouses
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Alternative nameAPRIL, Rec., Mouse (a expantion Inducing Ligand, TALL-2, tumor necrosis factor and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, tumor necrosis factor-related Death Ligand 1a, tumor necrosis factor (ligand) superfamily, member 13)
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Alternative techniquerec, murine
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Alternative to gene targettumor necrosis factor (ligand) superfamily, member 13, APRIL and CD256 and TALL-2 and TALL2 and TRDL-1 and ZTNF2, TNFSF13 and IDBG-25388 and ENSG00000161955 and 8741, protein binding, nuclei, Tnfsf13 and IDBG-488114 and ENSMUSG00000089669 and 69583, TNFSF13 and IDBG-635008 and ENSBTAG00000000130 and 100551513,538567
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Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 13
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 13
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor superfamily
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameacidic nuclear phosphoprotein 32 family member B
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Synonyms gene name
- acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2002-02-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ANP32 acidic nuclear phosphoproteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNFSF12-TNFSF13 readthrough
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-07-31
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF superfamily member 13b
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 13b
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data